Table 2 Adverse events
AE symptom (not mutually exclusive) | No. symptoms reported | No. patients |
|---|---|---|
Omalizumab | N = 17a | |
Skin (rash, erythema, wheals, eczema, urticaria/itching) | 8 | 4 |
Angioedema | 6 | 3 |
Anaphylaxis | 3 | 2 |
Headaches | 2 | 2 |
Hot/flushed | 2 | 2 |
Omalizumab reaction (not specified) | 1 | 1 |
Palpitations | 2 | 2 |
Pregnancy | 2 | 2 |
”Fuzzy head” | 1 | 1 |
Biliary colic | 1 | 1 |
Conjunctival haemorrhage | 1 | 1 |
Erectile dysfunction | 1 | 1 |
Hair loss | 1 | 1 |
Injection site reaction | 1 | 1 |
Sinus bradycardia | 1 | 1 |
Shortness of breath | 1 | 1 |
Tachycardia | 1 | 1 |
Type III Immune complex medicine reaction | 1 | 1 |
Total—omalizumab | 36 | – |
Ciclosporin | N = 28a | |
Hypertension | 8 | 8 |
Fatigue/tiredness | 6 | 6 |
GI | 4 | 4 |
Headaches | 4 | 4 |
Altered sensation | 3 | 2 |
Pregnancy | 2 | 2 |
Worsening renal function | 2 | 2 |
Dizziness/collapse | 2 | 2 |
Excess hair growth | 1 | 1 |
Increased ESR | 1 | 1 |
Lower back pain | 1 | 1 |
Loin pain | 1 | 1 |
Lumpectomy | 1 | 1 |
Memory problems | 1 | 1 |
Miscarriage | 1 | 1 |
Muscle weakness | 1 | 1 |
Side effects | 1 | 1 |
UTI | 1 | 1 |
Peripheral oedema | 1 | 1 |
Poor wound healing | 1 | 1 |
Mild stroke | 1 | 1 |
Urticarial flare | 1 | 1 |
Gum soreness and swelling | 1 | 1 |
Unwell | 1 | 1 |
Visual disturbance | 1 | 1 |
Seborrheic keratosis | 1 | 1 |
Total—ciclosporin | 49 | – |