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Fig. 1 | Allergy, Asthma & Clinical Immunology

Fig. 1

From: A rare nonsynonymous variant in the lipid metabolic gene HELZ2 related to primary biliary cirrhosis in Chinese Han

Fig. 1

Linkage disequilibrium of the region containing HELZ2. Upper panel showed the recombination rate (cM/Mb) (hg19, estimated using all populations of HapMap Phase 2: CEU Utah residents of Northern and Western European ancestry, JPT Japanese in Tokyo, Japan, CHB Han Chinese in Beijing, China, YRI Yoruba in Ibadan, Nigeria. Genetic recombination rates were represented by grey line, and genes within the region were shown in the middle panel. The lower panel showed the pairwise linkage disequilibrium between SNPs in this region. The color of each diamond represented the pairwise linkage between SNPs (measured as r2) defined by the upper left and the upper right sides of the diamond. Shading represented the magnitude of pairwise LD, with a red-to-white gradient reflecting higher to lower LD values

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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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