Fig. 1

Early asthmatic responses to the four allergen challenges. The data on the left (Placebo AC1 and AC2) depicts the absence of refractoriness. The data on the right shows the inhibitory effect of ibuprofen (ibuprofen AC1 versus placebo AC1) and the duration of the inhibition (ibuprofen AC1 versus ibuprofen AC2). Data are presented as the geometric mean allergen PC₂₀. Error bars represent the standard error of the mean SEM. The time interval between AC1 and AC2 for each treatment is 24 h