Table 3 Changes in markers of inflammation
From: Allergen inhalation challenge, refractoriness and the effects of ibuprofen
Treatment | Timepoint | Blood EOS (x109/L) | Sputum EOS (%) | FeNO (ppb) | MCh PC20 (mg/mL) |
|---|---|---|---|---|---|
Placebo | pre AC (baseline) | 0.17 (0.11–0.26) | 5.1 (2.7–9.6) | 29.5 (19.7–44.2) | 1.9 (0.95–3.8) |
7 h post AC1 | 0.20 (0.14–0.28) | 8.2 (3.1–21.9) | 33.2 (22.3–49.4) | 1.9 (0.95–4.1) | |
7 h post AC2 | 0.23 (0.16–0.34) | 12.1 (4.2–35.0) | 39.0 (25.4–59.9) | 1.7 (0.96–3.1) | |
Ibuprofen | pre AC= (baseline) | 0.14 (0.08–0.25) | 4.0 (2.1–7.8) | 29.7 (19.6–44.8) | 2.4 (0.99–5.8) |
7 h post AC1 | 0.21 (0.14–0.31) | 8.6 (3.4–21.8) | 30.5 (17.9–52.1) | 1.6 (0.70–3.5) | |
7 h post AC2 | 0.26 (0.18–0.39) | 14.1 (7.0–28.5) | 40.8 (24.4–68.3) | 1.5 (0.73–3.2) |