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Table 1 Baseline characteristics of participants

From: Day-time variation of serum periostin in asthmatic adults treated with ICS/LABA and adults without asthma

Variable N = 16

Mean (SD)

Median (IQR)

Min to max

Asthma

Age (years)

45.4 (19.7)

47 (25 to 63.5)

19–73

BMI (kg/m2)

32.2 (5.3)

33.4 (28.8–35.5)

20.9–42.2

FEV1 % predicteda

90.5 (18.1)

96.6 (81.9–102.9)

50.6–111.6

FEV1/FVC ratiob

0.82 (0.04)

0.81 (0.79–0.85)

0.77–0.89

Mean ICS dosec

489 (105.3)

500 (500–500)

200–500

Eosinophil count (×109/L)d

0.31 (0.20)

0.25 (0.20–0.35)

0–0.7

FeNO (ppb)

26.1 (13.3)

23.5 (16–36)

7–55

Periostin (ng/mL)

53.5 (13.6)

51.7 (41.5–63.7)

33.9–76.2

ACQ-5e

1.3 (1.2)

1.2 (0.4–1.4)

0–4.0

AQLQ(S)

5.71 (1.22)

6.05 (5.5–6.35)

2.8–7.0

Categorical variables

Number (%)

  

ACQ ≤ 0.75

5 (31)

  

ACQ ≥ 1.50

3 (19)

  

ACQ > 0.75 to <1.50

8 (50)

  

Atopyf (yes)

13 (81)

  

Female

12 (75)

  

Caucasian

12 (75)

  

Asian

1 (6)

  

Other

3 (19)

  

Variable N = 16

Mean (SD)

Median (IQR)

Min to max

Non-asthma

Age (years)

28.1 (12.7)

23 (21–30.5)

20–68

BMI (kg/m2)

23.8 (2.8)

22.8 (22.1–27.0)

19.7–28.3

FEV1 % predicteda

97.9 (10.5)

96.3 (90.8–105.7)

80.5–120.9

FEV1/FVC ratiob

0.85 (0.03)

0.86 (0.85–0.88)

0.77–0.88

Eosinophil count (×109/L)

0.19 (0.11)

0.20 (0.10–0.25)

0.10–0.50

FeNO (ppm)

22.3 (14.1)

19.5 (15.5–24.5)

6.0–68.0

Periostin (ng/mL)

50.5 (13.0)

49.4 (42.5–62.7)

28.6–70.5

Categorical variables

Number (%)

  

Atopy (yes)

5 (31)

  

Female

11 (69)

  

Caucasian

13 (81)

  

Other

3 (19)

  
  1. SD standard deviation, IQR interquartile ratio, BMI body mass index, ICS inhaled corticosteroid, FeNO fraction of exhaled nitric oxide
  2. aFEV1 post-bronchodilator, expressed as % of normal predicted values
  3. bFEV1/FVC ratio, pre-bronchodilator
  4. cICS daily dose expressed as fluticasone propionate equivalent (microg/day)
  5. dEosinophil laboratory reference range: 0.0–0.5 × 109/L, (measured in increments of 0.1)
  6. eACQ-5: asthma control questionnaire-5, a score >1.5 indicates uncontrolled asthma [26]
  7. fAtopy: a history of eczema and/or seasonal rhinitis