Fig. 5

Correlation of frequency of TIGIT-expressing CD3⁺CD4⁺ T lymphocytes with disease activity. a The frequency of TIGIT-expressing CD3⁺CD4⁺ T lymphocytes in SLE patients was significantly increased in active SLE patients compared to inactive SLE patients (P = 0.04). b The frequency of TIGIT-expressing CD3⁺CD4⁺ T lymphocytes in SLE patients correlated significantly with SLEADI (r² = 0.082; P = 0.044). c The frequency of TIGIT-expressing CD3⁺CD4⁺ T lymphocytes tends to be elevated in new-onset patients of SLE, but a significant difference was not reached (P = 0.28)