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Table 2 Demographic and clinical data for Chinese patients with active or inactive SLE

From: Elevated expression of TIGIT on CD3+CD4+ T cells correlates with disease activity in systemic lupus erythematosus

Categories

Active SLE

Inactive SLE

N

16

34

Females, n (%)

16 (100)

30 (88.2)

Age, mean (SD), years

32.8 (9.4)

36.7 (15.1)

ANA (+, ≥1:100), n (%)

16 (100)

33 (97.1)

Anti-dsDNA, mean (SD), IU/mL

355.8 (328.4)*

148.4 (239.9)

IgG, mean (SD), g/L

19.6 (9.8)

16.8 (7.9)

C3, mean (SD), g/L

0.45 (0.23)*

0.66 (0.26)

C4, mean (SD), g/L

0.11 (0.062)

0.14 (0.060)

ESR, mean (SD), mm/h

63.1 (44.1)

34.2 (35.5)

SLEDAI score, mean (SD)

12.6 (2.4)*

3.6 (2.8)

Lymphocytes, mean (SD), %a

12.0 (1.7)*

19.5 (1.9)

CD3+ lymphocytes, mean (SD), %b

73.2 (2.7)

68.2 (2.5)

CD4+ T subset, mean (SD), %c

42.5 (4.4)

47.3 (2.7)

CD4+ T subset, mean (SD), /mL

243.5 (69.6)

343.4 (38.2)

CD8+ T subset, mean (SD), %c

59.1 (4.0)

53.1 (2.6)

CD8+ T subset, mean (SD), /mL

336.1 (80.0)

455.1 (77.1)

Ratio of CD4+/CD8+ T, mean (SD)

0.81 (0.17)

1.12 (0.15)

  1. ANA anti-nuclear antibodies, Anti-dsDNA anti double-stranded DNA, C3 complement 3, C4 complement 4, ESR erythrocyte sedimentation rate, IgG immunoglobulin G, SLE systemic lupus erythematosus, SLEDAI SLE disease activity index
  2. * P < 0.05 compared to inactive SLE group
  3. aPercentage of total white blood cells in peripheral blood
  4. bPercentage of total lymphocytes in peripheral blood
  5. cPercentage of CD3+ lymphocytes in peripheral blood