Fig. 1From: Systemic mastocytosis with KIT V560G mutation presenting as recurrent episodes of vascular collapse: response to disodium cromoglycate and disease outcomeBone marrow cytological and histopathological features at diagnosis. a Leishman’s (A1), toluidine blue (A2) and chloroacetate esterase (A3) staining of bone marrow (BM) smears from the patient at diagnosis, revealing atypical mast cells (MCs) with elongated cytoplasmic extensions and abnormal granulation (*). A normal MC is shown for comparison (A1, **). b Hematoxilin-eosin (B1, 40×; B2, 400×), Giemsa staining (B3, 400×) and CD117 immunostaining (B4, 400×) of a BM trephine biopsy from the patient at diagnosis, showing normocellular marrow with osteosclerosis (B1, *) and scattered elongated and degranulated abnormal (B2 and B3, *), CD117 positive (B4) MCsBack to article page