Table 1 Propellant volumes from different pMDIs
From: Asthma pressurised metered dose inhaler performance: propellant effect studies in delivery systems
HFA 134a norflurane | Salamol, (IVAX) small | 490/70 puffs = 7 ml per puff |
Ventolin (A&H) large | 480/30 puffs = 16 ml per puff | |
Clenil Modulite™ (Chiesi) large | 400/35 puffs = 11.75 ml per puff | |
HFA 227ea apaflurane | Intal™ (Sanofi-Aventis) large | 465/35 puffs = 13.5 ml per puff |
Vannair™ (AstraZeneca) small | 480/53 puffs = 9 ml per puff | |
CFCa | Serevent™ (A&H) small | 530 ml/35 puffs = 15.6 ml per puff |
Ventolin ™ (A&H) large | 490/24 puffs = 20.4 ml per puff |