Fig. 7
From: Clinical implications of CD4+ T cell subsets in adult atopic asthma patients
Frequency of α4+ CD4+ T cells in atopic asthma patients correlates with clinical severity. a Representative FACS analysis of whole blood staining for α4 and CD11a in CD4+ T cells in non-asthmatic subjects (NAS) and asthma patients (AS). Gates based on isotype antibody staining pattern. b Frequency analysis of integrin-expressing cells in CD4+ and CD8+ T cells in NAS and AS. c Correlation analysis of the frequency and number of α4-expressing CD4+ T cells in AS with ACT score. d Representative FACS data of whole blood staining (left) and compiled frequency of α4+ in CD8+ T cells (right) in NAS and AS. Representative FACS data of whole blood staining and compiled frequencies of β7-expressing CD4+ T cells (e) and CD8+ T cells (f) in NAS and AS. *P < 0.05, **P < 0.01, ***P < 0.001. Error bars indicate SD