Table 1 List of histone modifications appearing in this review along with their effects on the transcriptional activity
From: Histone modifications and their role in epigenetics of atopy and allergic diseases
Modification and site | Abbreviation | Effect on transcriptiona |
|---|---|---|
Histone acetylation | ||
Histone 3 panacetylation | H3ac | Activating/permissive |
Histone 4 panacetylation | H4ac | Activating/permissiveb |
Histone 3 lysine 4 acetylation | H3K4ac | Activating/permissive |
Histone 3 lysine 9 acetylation | H3K9ac | Activating/permissive |
Histone 3 lysine 14 acetylation | H3K14ac | Activating/permissive |
Histone 3 lysine 18 acetylation | H3K18ac | Activating/permissive |
Histone 3 lysine 27 acetylation | H3K27ac | Activating/permissive |
Histone 4 lysine 16 acetylation | H4K16ac | Activating/permissive |
Histone methylation | ||
Histone 3 lysine 4 methylation | H3K4me1 | Activating/permissive |
Histone 3 lysine 4 dimethylation | H3K4me2 | Activating/permissive |
Histone 3 lysine 4 trimethylation | H3K4me3 | Activating/permissive |
Histone 3 lysine 9 dimethylation | H3K9me2 | Repressive |
Histone 3 lysine 9 trimethylation | H3K9me3 | Repressive |
Histone 3 lysine 27 trimethylation | H3K27me3 | Repressive |
Histone 3 lysine 36 trimethylation | H3K36me3 | Activating/permissive |
Histone 3 lysine 79 methylation | H3K79me1 | Activating/permissive |
Histone phosphorylation | ||
Histone 3 serine 10 phosphorylation | H3S10ph | Activating/permissive |
Histone ubiquitination | ||
Histone 2A ubiquitination | H2Aub | Repressive |
Histone 2B ubiquitination | H2Bub | Activating/permissive |