Fig. 3

Histological analysis of allergic airway inflammation by immunohistochemical (IHC) staining. a, d Image representative of the negative control from normal mice. b, e Image representative of the positive control from the HDM-sensitized mice that received following challenge with HDM extractrs. c, f Image representative of the HDM group that HDM-sensitized mice received oral immunotherapy with HDM extracts ingestion before the challenge. There were numerous inflammatory cells that had infiltrated beneath the tracheal epithelium in the PC and HDM groups. Representative photomicrographs of different groups are shown; n = 5 mice per group