Table 1 Classification of adverse drug reactions [1, 4, 5]
From: Drug allergy
Type A: predictable | Type B: unpredictable |
|---|---|
•Drug overdose •Secondary drug effects •Side effects •Drug interactions | •Drug allergy: an immunologically mediated ADR •Pseudoallergic (non-allergic): a reaction with the same clinical manifestations as an allergic reaction, but that lacks immunological specificity •Drug intolerance: an undesirable pharmacologic effect that occurs at low and sometimes sub-therapeutic doses of the drug that are not caused by underlying abnormalities of metabolism or drug excretion •Drug idiosyncrasy: an abnormal/unexpected effect, usually caused by underlying abnormalities of metabolism, excretion, or bioavailability |