Aberrant localization of FOXJ1 correlates with the disease severity and comorbidities in patients with nasal polyps

Table 1 Summary characteristics of the study participants

	Controls	Patients with CRSwNP
Sample size [no.]	40	111
Age, years (mean ± SD)	33.3 ± 10.7	42.6 ± 16.6
Gender (M/F)	25/15	79/32
AR [no. (%)]^a	0 (0)	40 (36.0)
Asthma [no. (%)]^a	0 (0)	28 (25.2)
Lund–Mackay CT scores (mean ± SD)^b	NA	15.3 ± 4.4
Detection methods
Paraffin specimens [no.]^c	20	83
AR [no. (%)]	0 (0)	31 (37.3)
Asthma [no. (%)]	0 (0)	18 (21.7)
qRT-PCR [no.]	34	77
AR [no. (%)]	0 (0)	25 (32.5)
Asthma [no. (%)]	0 (0)	20 (26.0)
Cytospin preparations [no.]	4	6

AR allergic rhinitis, CRSwNP chronic rhinosinusitis with nasal polyp, CT computed tomography, F female, M male, SD standard deviation, NA not applicable
^aNone of the patients had co-existing allergic rhinitis with asthma been included
^bCT scores were recorded in 54 patients with CRSwNP
^cHematoxylin–eosin staining, immunohistochemistry staining and immunofluorescence staining were performed in the same paraffin specimens from 20 control subjects and 83 patients with CRSwNP

ISSN: 1710-1492