Fig. 3
From: Melkersson–Rosenthal syndrome: a case report of a rare disease with overlapping features
Histological aspects. a Lip biopsy showed the inflammatory infiltrate in the submucosa associated with numerous granulomas (H&E staining, magnification ×25). b, c Higher magnification of the granulomas in the deep submucosa, showing giant cells and lymphoplasma cells, without non-caseating necrosis (H&E staining, magnification ×80). d Giant cells of macrophage origin as confirmed by an antimacrophage antibody staining, CD68 (magnification ×80)