Fig. 3From: IL2RG hypomorphic mutation: identification of a novel pathogenic mutation in exon 8 and a review of the literatureJAK3-STAT5 signaling pathway in patients with atypical X-SCID. Expression of activated JAK3 and STAT5, as well as total JAK3, JAK3* (reprobe with anti-JAK3 antibody binding to the kinase domain), STAT5, IL2R and GAPDH in unstimulated or IL2 stimulated cells, were evaluated by Western blotBack to article page