Fig. 1

a Changes in wheeze prevalence by the deciles of genetic risk score estimated based on 19 risk variants identified in this study. Increase in wheeze prevalence is strongly associated with increase in genetic risk score (pval: 1.38e−10). b Comparison between breastfed and non-breastfed group at 12 months show that wheeze prevalence is higher among those with lower genetic risk vs. those who were breastfed. However, the beneficial effects of breastfeeding are not evident among those subjects with the highest genetic risk