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Table 1 Resource use for SQ HDM SLIT-tablet and HDM SCIT (Ontario and Quebec)

From: Sublingual immunotherapy tablet for the treatment of house dust mite allergic rhinitis in Canada: an alternative to minimize treatment costs?

Resource

Ontario

Quebec

SQ HDM SLIT-tablet

HDM SCIT

SQ HDM SLIT-tablet

HDM SCIT

Year 1

Year 2

Year 3

Year 1

Year 2

Year 3

Year 1

Year 2

Year 3

Year 1

Year 2

Year 3

10 mL viala (10 inj.)

3.1

1.3

1.3

3.1

1.3

1.3

SQ HDM SLIT-tablet (package with 30 tablets)

12

12

12

12

12

12

Start-up visits

1

1

1

 GP (Ontario 20%, Quebec 5%)a

0.2

0.05

0.05

 Specialist (Ontario 80%, Quebec 95%)a

0.8

0.95

0.95

Titration visits (1 week between inj. [15])

24

24

 GP (Ontario 20%, Quebec 95%)a

4.8

22.8

 Specialist (Ontario 80%, Quebec 5%)a

19.2

1.2

Maintenance visits (4 weeks between inj. [15])

7

13

13

7

13

13

 GP (95%)a

6.65

12.35

12.35

6.65

12.35

12.35

 Specialist (5%)a

0.35

0.65

0.65

0.35

0.65

0.65

Nurse time ([h]; Ontario 0.5 per inj., Quebec 0.75 per inj.)a

15.5

6.5

6.5

23.25

9.75

9.75

Nurse time ([h]; 0.75 per start-up, tablet/only Quebec)

0.75

Follow-up visits

1

1

1

1

1

1

1

1

1

1

1

1

 GP (Ontario 50% SLIT, 20% SCIT; Quebec 50%)a

0.5

0.5

0.5

0.2

0.2

0.2

0.5

0.5

0.5

0.5

0.5

0.5

 Specialist (Ontario 50% SLIT, 80% SCIT; Quebec 50%)a

0.5

0.5

0.5

0.8

0.8

0.8

0.5

0.5

0.5

0.5

0.5

0.5

Patient’s time [h]a [15]

3c

1.25c

1.25c

57.57b

24.87b

24.87b

3c

1.25c

1.25c

48.48b

20.53b

20.53b

Patient’s travel distance ([km]; 20 km per visit) [15]

40

20

20

620

260

260

40

20

20

660

280

280

  1. GP general practitioner, HDM SCIT house dust mite subcutaneous immunotherapy, inj. injection, SQ HDM SLIT-tablet SQ house dust mite sublingual immunotherapy tablet
  2. aBased on physician input, b Patient’s time include: travel time round trip 40 min [15], wait time 15 min [15], injection time 4 mina, post-injection time 30 min [15], physician consultation time 20 mina, c Patient’s time include: Travel time round trip 40 min [15], wait time 15 min [15], physician consultation time 20 mina, and for year 1 only a 30 min post-tablet observational time after first tablet intake [28]