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Table 2 The comparison of wheezing risk factors between the three wheezing phenotypes

From: Risk factors and prognosis of recurrent wheezing in Chinese young children: a prospective cohort study

  Transient wheezing (n = 14) Persistent wheezing (n = 54) Late-onset wheezing (n = 17) Statistics p
Information from recruitment
Total virus positive [n (%)] 6 (42.9) 28 (51.9) 5 (29.4) χ2= 2.68 0.281
RV positive [n (%)]a 2 (14.3) 20 (37.0) 3 (17.6) χ2= 3.85 0.150
RSV positive [n (%)]a 1 (7.1) 8 (14.8) 1 (5.9) χ2= 0.91 0.703
PIV positive [n (%)]a 2 (14.3) 3 (5.6) 0 (0.0) χ2= 2.45 0.239
hMPV positive [n (%)]a 0 (0.0) 0 (0.0) 1 (5.9) χ2= 3.43 0.365
Bocavirus positive [n (%)]a 0 (0.0) 1 (1.9) 0 (0.0) χ2= 1.12 1.000
Flu positive [n (%)]a 1 (7.1) 0 (0.0) 0 (0.0) χ2= 3.82 0.165
Serum IgE test (n = 45) n = 7 n = 29 n = 9   
Total IgE (ku/L) 59.8 ± 35.1 193.7 ± 206.4 237.7 ± 202.7
Log transformed total IgE 0.7 ± 0.4 2.1 ± 0.4 2.3 ± 0.3 F = 5.03 0.011
Atopy 4 (57.1) 24 (82.8) 9 (100.0) F = 4.36 0.076
Aeroallergens positive (Phad) [n (%)]a 1 (14.3) 11 (37.9) 7 (77.8) χ2= 6.71 0.031
Mould mix positive (MX1) (n = 38)a 1 (16.7) 6 (25.0) 5 (62.5) χ2= 4.16 0.128
House dust mite positive (HDM) (n = 37)a 0 (0.0) 7 (30.4) 4 (50.0) χ2= 3.88 0.167
Food allergens positive [n (%)]a 2 (28.6) 15 (51.7) 5 (55.6) χ2= 1.39 0.623
 EOS in peripheral blood (n = 68) n = 10 n = 44 n = 14   
 Percentage (%) 2.60 ± 2.54 3.65 ± 2.41 5.06 ± 2.27 F = 3.24 0.045
 Absolute count (× 109/L) 0.27 ± 0.24 0.39 ± 0.30 0.49 ± 0.30 F = 2.56 0.085
Parental asthma history [n (%)]a 1 (7.1) 5 (9.3) 1 (5.9) χ2 = 0.23 1.000
Information from follow-up
Rhinitis ever [n (%)] 2 (14.3) 34 (63.0) 15 (88.2) χ2 = 18.00 0.000
Current rhinitis [n (%)] 2 (14.3) 27 (50.0) 10 (58.8) χ2 = 7.14 0.028
Eczema ever [n (%)] 8 (57.1) 36 (66.7) 10 (58.8) χ2 = 0.64 0.727
Current eczema [n (%)]a 1 (7.1) 7 (13.0) 3 (17.6) χ2 = 0.74 0.804
  1. Italic values indicate the significance of p value (p < 0.05)
  2. aFisher’s exact test was used for groups’ comparison