Table 2 The comparison of wheezing risk factors between the three wheezing phenotypes

Information from recruitment

Total virus positive [n (%)]

6 (42.9)

28 (51.9)

5 (29.4)

χ²= 2.68

RV positive [n (%)]^a

2 (14.3)

20 (37.0)

3 (17.6)

χ²= 3.85

RSV positive [n (%)]^a

1 (7.1)

8 (14.8)

1 (5.9)

χ²= 0.91

PIV positive [n (%)]^a

2 (14.3)

3 (5.6)

0 (0.0)

χ²= 2.45

hMPV positive [n (%)]^a

0 (0.0)

0 (0.0)

1 (5.9)

χ²= 3.43

Bocavirus positive [n (%)]^a

0 (0.0)

1 (1.9)

0 (0.0)

χ²= 1.12

Flu positive [n (%)]^a

1 (7.1)

0 (0.0)

0 (0.0)

χ²= 3.82

Serum IgE test (n = 45)

n = 7

n = 29

n = 9

Total IgE (ku/L)

59.8 ± 35.1

193.7 ± 206.4

237.7 ± 202.7

–

–

Log transformed total IgE

0.7 ± 0.4

2.1 ± 0.4

2.3 ± 0.3

F = 5.03

Atopy

4 (57.1)

24 (82.8)

9 (100.0)

F = 4.36

Aeroallergens positive (Phad) [n (%)]^a

1 (14.3)

11 (37.9)

7 (77.8)

χ²= 6.71

Mould mix positive (MX1) (n = 38)^a

1 (16.7)

6 (25.0)

5 (62.5)

χ²= 4.16

House dust mite positive (HDM) (n = 37)^a

0 (0.0)

7 (30.4)

4 (50.0)

χ²= 3.88

Food allergens positive [n (%)]^a

2 (28.6)

15 (51.7)

5 (55.6)

χ²= 1.39

 EOS in peripheral blood (n = 68)

n = 10

n = 44

n = 14

 Percentage (%)

2.60 ± 2.54

3.65 ± 2.41

5.06 ± 2.27

F = 3.24

 Absolute count (× 10⁹/L)

0.27 ± 0.24

0.39 ± 0.30

0.49 ± 0.30

F = 2.56

Parental asthma history [n (%)]^a

1 (7.1)

5 (9.3)

1 (5.9)

χ² = 0.23

Information from follow-up

Rhinitis ever [n (%)]

2 (14.3)

34 (63.0)

15 (88.2)

χ² = 18.00

Current rhinitis [n (%)]

2 (14.3)

27 (50.0)

10 (58.8)

χ² = 7.14

Eczema ever [n (%)]

8 (57.1)

36 (66.7)

10 (58.8)

χ² = 0.64

Current eczema [n (%)]^a

1 (7.1)

7 (13.0)

3 (17.6)

χ² = 0.74