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Table 1 Characteristics of the study population at baseline

From: Clinical and pulmonary function changes in cough variant asthma with small airway disease

  CVA with low FEF50% (n = 27) CVA with normal FEF50% (n = 30) p value
Age (years) 43.2 ± 14.1 41.1 ± 15.6 0.33
Gender (male: female) 56%/44% 27%/73% 0.48
Medical history
 Daytime cough 11 (40.7%) 6 (20%) 0.33
 Nighttime cough 19 (70.4%) 23 (77.6%) 0.68
 Cough affects sleep 19 (70.4%) 15 (50.0%) 0.57
 Chest tightness 20 (74.1%) 10 (33.3%) 0.40
 Allergic rhinitis 17 (62.9%) 22 (73.3%) 0.15
 Allergic family history 15 (55.6%) 15 (50.0%) 0.27
Pulmonary function test
 FEV1/FVC (%) 77.4 ± 6.06 86.0 ± 6.12 < 0.001
 FEV1% 90.77 ± 11.4 99.8 ± 13.6 0.97
 FEF50% 62.95 ± 8.06 85.7 ± 16.7 < 0.001
Asthma control assessments
 ACT 17.9 ± 4.4 18.3 ± 3.0 0.57
 ACQ 1.79 ± 0.99 1.43 ± 0.66 0.14
Induced sputum
 Total number of cells (105/mL) 5.6 ± 1.2 6.7 ± 0.9 0.45
 Neutrophils (%) 30.5 ± 6.2 47.2 ± 10.9 0.67
 Eosinophils (%) 3.6 ± 0.2 2.7 ± 0.4 0.55
 Lymphocytes (%) 7.8 ± 0.6 9.2 ± 0.2 0.23
 Macrophages (%) 36.4 ± 4.2 32.3 ± 3.3 0.78