Table 2 Comparison of the expression of 5-LOX, COX-1, COX-2 and \(\hbox {CysLT}_2\) between the respiratory epithelium, the submucosal glands and the squamous epithelium
RE; mean (SE) | SG mean (SE) | SEP mean (SE) | p-value RE vs. SG | p-value SEP vs. SG | p-value RE vs. SEP | |
|---|---|---|---|---|---|---|
5-LOX nasal polyps | 9.645 (1.197) | 13.588 (1.241) | 9.42 (1.59) | 0.038 | 0.094 | NS |
5-LOX bronchial tissue | 7.266 (1.458) | 15.901 (1.778) | 6.915 (1.516) | 0.001 | 0.001 | NS |
COX-1 nasal polyps | 13.287 (1.82) | 10.24 (1.42) | 13.784 (1.774) | 0.001 | 0.003 | NS |
COX-1 bronchial tissue | 10.611 (1.912) | 5.103 (1.959) | 11.83 (2.077) | 0.028 | 0.003 | NS |
COX-2- nasal polyps | 21.245 (1.335) | 13.763 (0.978) | 20.959 (1.494) | < 0.001 | < 0.001 | NS |
COX-2 bronchial tissue | 14.47 (1.898) | 7.406 (1.581) | 13.794 (1.947) | 0.002 | 0.011 | NS |
\(\hbox {CysLT}_2\) nasal polyps | 3.041 (0.895) | 18.851 (1.125) | 3.078 (0.895) | < 0.001 | < 0.001 | NS |
\(\hbox {CysLT}_2\) bronchial tissue | 1.938 (0.851) | 13.969 (1.841) | 1.936 (0.581) | < 0.001 | < 0.001 | NS |