Table 2 Lymphocytes subsets and immunoglobulin of STAT3 mutation patients

Lymphocytes subsets

 Total T cells (cells/μL)

2418.05↑ (1325–2276)

1640.43 (1325–2276)

2210.10 (1480–2847)

4180.60↑ (1775–3953)

3722.60 (1794–4247)

2748.03 (1775–3953)

2198.60 (1325–2276)

2484.20 (2187–6352)

1704.50 (1424–2664)

1524.7 (1775–3953)

3343.50 (2187–6352)

665.20↓ (1169–2071)

 Total T cells (%)

79.79↑ (57.10–73.43)

72.59 (57.10–73.43)

72.99 (59.50–75.56)

71.41 (53.37–71.91)

65.59 (53.88–72.87)

64.26 (53.37–71.91)

77.67↑ (57.10–73.43)

60.47 (55.32–73.11)

74.92 (60.05–74.08)

59.09 (53.37–71.91)

60.88 (55.32–73.11)

79.77↑ (61.29–73.13)

 CD4 T cells (cells/μL)

935.32 (531–1110)

859.30 (531–1110)

1537.59 (767–1592)

2784.37↑ (948–2477)

2073.18 (902–2253)

1900.82 (948–2477)

1346.17↑ (531–1110)

1403.91 (1125–3768)

936.74 (686–1358)

833.11 (948 –2477)

1812.96 (1125–3768)

347.24↓ (554–1109)

 CD4 T cells (%)

30.98 (24.00–38.72)

37.96 (24.00–38.72)

50.78↑ (28.49–41.07)

47.56↑ (26.19–45.48)

37.38 (24.08–42.52)

45.86 (26.19–45.48)

47.56↑ (24.00–38.72)

34.17 (28.17–47.74)

41.17 (26.17–40.76)

32.29 (26.19–45.48)

33.01 (28.17–47.74)

39.03 (26.36–40.90)

 CD8 T cells (cells/μL)

1133.59 (480–1112)

579.86 (480–1112)

620.54 (553–1127)

1291.87 (531–1521)

1480.57 (580–1735)

766.79 (531–1521)

757.71 (480–1112)

934.42 (686–2278)

521.27 (518–1125)

614.41 (531–1521)

1299.38 (686–2278)

265.24↓ (423–900)

 CD8 T cells (%)

37.26↑ (21.01–33.94)

25.29 (21.01–33.94)

20.49 (19.70–32.04)

22.07 (16.29–29.88)

25.38 (19.00–32.51)

16.60 (16.29–29.88)

26.77 (21.01–33.94)

22.74 (15.88–31.48)

22.91 (19.68–34.06)

23.81 (16.29–29.88)

23.66 (15.88–31.48)

35.13↑ (20.99–33.73)

 Total B cells (cells/μL)

334.16 (216–536)

228.69 (216–536)

719.88 (303.52–777.25)

1238.04 (537.11–1464.39)

1500.17↑ (461–1456)

1320.16 (537.11–1464.39)

560.52↑ (216–536)

957.21 (916–1832)

366.17 (280–623)

801.72 (537.11–1464.39)

1732.5 (916–1832)

116.07↓ (176.56–415.64)

 Total B cells(%)

11.23 (9.19–19.48)

11.96 (9.19–19.48)

23.78↑ (10.46–21.77)

21.15 (13.93–30.49)

26.67 (13.23–26.39)

28.15 (13.93–30.49)

19.80 (9.19–19.48)

23.30 (17.20–29.71)

16.09 (10.21–20.12)

31.07 (13.93–30.49)

31.55↑ (17.20–29.71)

16.24 (7.73–16.84)

 NK cells (cells/μL)

245.275 (246–792)

306.80 (246–792)

64.19↓ (227–668)

373.53 (241–978)

386.41 (270–1053)

329.45 (241–978)

17.08↓ (246–792)

597.21 (306–896)

190.56↓ (258–727)

208.92↓ (241–978)

384.33 (306–896)

32.05↓ (232–789)

 NK cells(%)

8.23 (10.01–26.98)

14.31 (10.01–26.98)

2.12↓ (7.83–20.99)

6.38↓ (6.53–22.24)

6.53↓ (7.21–20.90)

6.03↓ (6.53–22.24)

0.60↓ (10.01–26.98)

14.53 (5.67–15.90)

8.38↓ (9.00–22.24)

8.1 (6.53–22.24)

7.00 (5.67–15.90)

2.85↓ (11.43–27.57)

CD4/CD8

0.84 (0.81–1.66)

1.53 (0.81–1.66)

2.48↑ (1.02–2.05)

2.16 (1.05–2.53)

1.52 (0.90–2.13)

2.85 (1.05–2.53)

1.78↑ (0.81–1.66)

1.50 (0.93–2.52)

1.80 (0.87–1.94)

1.36 (1.05–2.53)

1.4 (0.93–2.52)

1.32 (0.85–1.76)

Immunoglobulin

 IgG (g/L)

13.90

9.10

17.1↑

9.70

9.90

9.20

14.00

7.30

12.60

11.90

7.00

14.50

 IgA (g/L)

1.16

1.15

2.76↑

0.63

0.56

0.18

0.32

0.16

1.27

0.71

0.18

1.30

 IgM (g/L)

1.07

0.86

1.23

2.32

1.36

0.72

1.99

0.77

1.51

1.23

0.37

1.84

 IgE (KU/L)

21,705.67↑↑↑

13,472.28↑↑↑

2660.19↑↑

6336.65↑↑

5021.83↑↑

3709.67↑↑

9015.51↑↑

67.2

17,310.4↑↑↑

1841.29↑↑

43.87

221.65↑