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Table 2 Comparison of obstetric outcomes between sensitized children and general population

From: Analysis of maternal and perinatal determinants of allergic sensitization in childhood

Infant related factors

Sensitized children (n = 286)

Rest of population (n = 66,583)

 

n

  

n

  

P

Sex (Male)

286

171

59.8%

66,576

34,327

51.6%

0.005*

Season of birth

286

  

66,583

  

0.806*

Spring

 

66

23.1%

 

16,241

24.4%

 

Summer

 

66

23.1%

 

16,086

24.2%

 

Autumn

 

73

25.5%

 

17,005

25.5%

 

Winter

 

81

28.3%

 

17,251

25.9%

 

Preterm (Yes)

286

19

6.6%

66,583

7701

11.6%

0.009*

Breastfed (Yes)

250

208

83.2%

49,619

38,431

77.5%

0.030*

Birth weight (kg)

286

3.395

± 0.591

66,574

3.305

± 0.685

0.011**

Birth length (cm)

279

50.5

± 3.4

64,870

50.3

± 3.9

0.279**

Birth HC (cm)

280

34.5

± 2.1

65,220

34.3

± 2.3

0.053**

z-score birth weight

286

0.062

± 1.014

65,852

0.007

± 1.072

0.387**

z-score birth length

279

0.154

± 1.109

63,933

0.134

± 1.184

0.780**

z-score birth HC

280

0.022

± 0.974

64,455

0.007

± 1.075

0.798**

Pregnancy related factors

 Conception (assisted)

242

20

8.3%

48,861

1960

4.0%

0.001*

 TPL (yes)

250

9

3.6%

50,066

2403

4.8%

0.639*

 Medical problem during pregnancy (yes)

252

11

4.4%

50,242

1934

3.8%

0.671*

 Resuscitation intervention (yes)

251

84

33.5%

50,303

15,752

31.3%

0.463*

 Delivery techniques used (yes)

251

14

5.6%

50,302

2206

4.4%

0.358*

 Mode of birth (CS)

251

94

37.5%

50,302

17,188

34.2%

0.274*

 Multiple birth (yes)

286

10

3.5%

66,583

2610

3.9%

0.713*

Maternal factors

 Gravidity

286

1

(0–2)

66,575

2

(1–3)

< 0.001***

 Parity

286

1

(0–1)

66,579

1

(0–2)

0.001***

 BMI (kg/m2)

243

  

49,106

  

0.017*

  Underweight (< 18.5)

 

33

13.6%

 

5234

10.7%

 

  Normal (18.5–24.9)

 

120

49.4%

 

20,119

41.0%

 

  Overweight (25–29.9)

 

49

20.2%

 

11,531

23.5%

 

  Obesity class I (30–34.9)

 

24

9.9%

 

6676

13.6%

 

  Obesity class II (35–39.9)

 

9

3.7%

 

3193

6.5%

 

  Obesity class III (≥ 40)

 

8

3.3%

 

2353

4.8%

 

 Age at delivery (years)

286

  

66,582

  

0.001*

  < 20

 

13

4.5%

 

4382

6.6%

 

  20–35

 

211

73.8%

 

52,801

79.3%

 

  > 35

 

62

21.7%

 

9399

14.1%

 

 Diabetes (Yes)

286

19

6.6%

66,583

3988

6.0%

0.642*

 Smoking (Yes)

242

24

9.9%

48,920

10,348

21.2%

< 0.001*

 Alcohol consumption (Yes)

242

1

0.4%

48,797

877

1.8%

0.139****

 Illegal drug use (Yes)

242

3

1.2%

48,861

1133

2.3%

0.387****

 Born in Australia (Yes)

286

201

70.3%

66,578

50,849

76.4%

0.015*

  1. The following binary variables are defined as: sex, male or female; type of conception, spontaneous or assisted; mode of birth, vaginal or CS. All other binary variables were defined as yes or no. BMI categories are according to WHO. Values are displayed as either n (%), median (IQR) or mean ± SD
  2. HC head circumference, TPL threatened premature labour, CS caesarean section
  3. * Chi-square test; ** t-test; *** Mann–Whitney U test; **** Fishers exact test