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Table 2 Comparison of obstetric outcomes between sensitized children and general population

From: Analysis of maternal and perinatal determinants of allergic sensitization in childhood

Infant related factors Sensitized children (n = 286) Rest of population (n = 66,583)  
n    n    P
Sex (Male) 286 171 59.8% 66,576 34,327 51.6% 0.005*
Season of birth 286    66,583    0.806*
Spring   66 23.1%   16,241 24.4%  
Summer   66 23.1%   16,086 24.2%  
Autumn   73 25.5%   17,005 25.5%  
Winter   81 28.3%   17,251 25.9%  
Preterm (Yes) 286 19 6.6% 66,583 7701 11.6% 0.009*
Breastfed (Yes) 250 208 83.2% 49,619 38,431 77.5% 0.030*
Birth weight (kg) 286 3.395 ± 0.591 66,574 3.305 ± 0.685 0.011**
Birth length (cm) 279 50.5 ± 3.4 64,870 50.3 ± 3.9 0.279**
Birth HC (cm) 280 34.5 ± 2.1 65,220 34.3 ± 2.3 0.053**
z-score birth weight 286 0.062 ± 1.014 65,852 0.007 ± 1.072 0.387**
z-score birth length 279 0.154 ± 1.109 63,933 0.134 ± 1.184 0.780**
z-score birth HC 280 0.022 ± 0.974 64,455 0.007 ± 1.075 0.798**
Pregnancy related factors
 Conception (assisted) 242 20 8.3% 48,861 1960 4.0% 0.001*
 TPL (yes) 250 9 3.6% 50,066 2403 4.8% 0.639*
 Medical problem during pregnancy (yes) 252 11 4.4% 50,242 1934 3.8% 0.671*
 Resuscitation intervention (yes) 251 84 33.5% 50,303 15,752 31.3% 0.463*
 Delivery techniques used (yes) 251 14 5.6% 50,302 2206 4.4% 0.358*
 Mode of birth (CS) 251 94 37.5% 50,302 17,188 34.2% 0.274*
 Multiple birth (yes) 286 10 3.5% 66,583 2610 3.9% 0.713*
Maternal factors
 Gravidity 286 1 (0–2) 66,575 2 (1–3) < 0.001***
 Parity 286 1 (0–1) 66,579 1 (0–2) 0.001***
 BMI (kg/m2) 243    49,106    0.017*
  Underweight (< 18.5)   33 13.6%   5234 10.7%  
  Normal (18.5–24.9)   120 49.4%   20,119 41.0%  
  Overweight (25–29.9)   49 20.2%   11,531 23.5%  
  Obesity class I (30–34.9)   24 9.9%   6676 13.6%  
  Obesity class II (35–39.9)   9 3.7%   3193 6.5%  
  Obesity class III (≥ 40)   8 3.3%   2353 4.8%  
 Age at delivery (years) 286    66,582    0.001*
  < 20   13 4.5%   4382 6.6%  
  20–35   211 73.8%   52,801 79.3%  
  > 35   62 21.7%   9399 14.1%  
 Diabetes (Yes) 286 19 6.6% 66,583 3988 6.0% 0.642*
 Smoking (Yes) 242 24 9.9% 48,920 10,348 21.2% < 0.001*
 Alcohol consumption (Yes) 242 1 0.4% 48,797 877 1.8% 0.139****
 Illegal drug use (Yes) 242 3 1.2% 48,861 1133 2.3% 0.387****
 Born in Australia (Yes) 286 201 70.3% 66,578 50,849 76.4% 0.015*
  1. The following binary variables are defined as: sex, male or female; type of conception, spontaneous or assisted; mode of birth, vaginal or CS. All other binary variables were defined as yes or no. BMI categories are according to WHO. Values are displayed as either n (%), median (IQR) or mean ± SD
  2. HC head circumference, TPL threatened premature labour, CS caesarean section
  3. * Chi-square test; ** t-test; *** Mann–Whitney U test; **** Fishers exact test