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Table 1 Summary of mast cell counts in external solutions containing caffeine or catechin

From: Catechin synergistically potentiates mast cell-stabilizing property of caffeine

Substances Degranulating mast cell counts/view All mast cell counts/view Degranulating mast cell ratio (%)
External solution (control) 26.0 ± 3.30 27.4 ± 4.01 95.4 ± 7.70
 1 mM caffeine 84.3 ± 13.7 86.2 ± 14.7 97.9 ± 1.50
 5 mM caffeine 59.8 ± 17 61.8 ± 17.7 96.6 ± 2.88
 10 mM caffeine 30.9 ± 14.9 46.7 ± 9.26 64.7 ± 23.3
 25 mM caffeine 10.8 ± 3.99 49.6 ± 9.19 21.8 ± 6.96
 50 mM caffeine 5.10 ± 2.28 36.0 ± 15.0 14.3 ± 3.70
 100 mM caffeine 4.90 ± 2.64 45.2 ± 13.5 11.1 ± 5.62
External solution (control) 42.5 ± 8.67 43.5 ± 8.78 97.7 ± 2.56
 1 mM catechin 81.2 ± 12.7 87.0 ± 14.3 93.5 ± 3.23
 2.5 mM catechin 35.0 ± 5.21 39.0 ± 6.32 90.0 ± 3.83
 5 mM catechin 50.0 ± 7.16 60.0 ± 11.1 84.1 ± 6.47
 10 mM catechin 33.5 ± 10.1 43.2 ± 12.4 77.4 ± 9.18
 25 mM catechin 17.8 ± 6.70 49.7 ± 10.4 35.5 ± 10.7
External solution (control) 66.8 ± 19.1 68.5 ± 19.0 97.4 ± 1.80
 10 mM caffeine 17.7 ± 13.8 35.7 ± 10.7 46.2 ± 26.1
 10 mM caffeine + 1 mM catechin 16.6 ± 10.8 72.6 ± 22.3 22.4 ± 10.9
 10 mM caffeine + 2.5 mM catechin 14.2 ± 4.66 58.3 ± 15.3 24.9 ± 8.38
  1. Values are means ± SD