Related ocular disease | Ocular signs |
---|---|
Allergic | |
 Atopic keratoconjunctivitis | Eyelid atopic dermatitis often present Conjunctival injection and chemosis Conjunctival scarring Giant papillae may be present Infiltration of the limbus (region where the cornea meets the sclera) and cornea [15] |
 Vernal keratoconjunctivitis | Tearing, profuse mucous discharge [28] Bulbar conjunctival injection Large papillae of superior palpebral conjunctiva, ‘cobblestone-like’ Corneal plaque/shield ulcer Trantas’ dots (infiltrates at the juncture of the cornea and the sclera) Corneal neovascularization and scarring |
 Atopic dermatitis | Periocular scaly, dry skin Eyelid thickening Lash loss Papillary hypertrophy of palpebral conjunctiva May be accompanied by conjunctival injection, watery/mucoid discharge [28] |
 Demodex-associated conjunctivitis (hypersensitivity to lid mites) | Heavy lash debris (lash collarettes) Bulbar conjunctival injection, may show papillae Eyelid hyperemia |
Others | |
 Contact-lens associated papillary conjunctivitis, CLPC (often termed Giant papillary conjunctivitis, GPC) | Mucoid discharge Excessive movement of contact lenses Papillary hypertrophy of superior palpebra conjunctiva; if severe: lid swelling, ptosis [28] Clear cornea |
 Anterior blepharitis (staphylococcal, seborrheic)  Posterior blepharitis (Meibomian gland dysfunction, ocular rosacea) | Lash debris, lid hypertrophy/hyperemia [15] Conjunctival injection and staining (lissamine green) Corneal staining (fluorescein) Evaporative dry eye disease |
 Dry eye disease (aqueous deficiency, evaporative) | Inadequate tear volume (low tear meniscus) (aqueous deficiency) Lash debris, lid hypertrophy/hyperemia, Meibomian gland dysfunction, ocular rosacea (poor tear film stability; evaporative dry eye) Conjunctival injection [15] and staining (lissamine green) Conjunctival chalasis (redundancy of the conjunctiva from loss of adherence to the sclera) Corneal staining (fluorescein) |
 Ocular toxicity (due to ophthalmic agents, usually preservatives) | Conjunctival injection Corneal staining |
 Others: e.g. superior limbic keratoconjunctivitis, floppy eyelid syndrome, etc. | Chronic symptoms and signs, some of which may overlap with AC |