From: Can eosinophilia and neutrophil–lymphocyte ratio predict hospitalization in asthma exacerbation?
Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
Crude OR (95% CI) | P | Adjusted OR (95% CI) | P | |
Gender, female | 1.87 (1.07–3.28) | 0.029 | 1.96 (0.98–3.91) | 0.057 |
Not using an asthma action plan | 2.15 (1.2–3.84) | 0.01 | 2.22 (1.09–4.49) | 0.027 |
Atopy status | 1.13 (0.63–2.02) | 0.674 | – | – |
Cause of the exacerbation | ||||
Infection versus non-infectious cause | 1.53 (0.85–2.73) | 0.153 | 1.65 (0.81–3.36) | 0.169 |
Allergen versus non-allergenic cause | 0.58 (0.19–1.72) | 0.323 | – | – |
Non-adherence to prescribed therapy versus adherence | 0.87 (0.45–1.68) | 0.671 | – | – |
Duration of asthma | ||||
< 1 year versus > 1 year | 0.69 (0.37–1.27) | 0.233 | – | – |
1–2 years versus < 1 year and > 2 years | 1.04 (0.57–1.87) | 0.904 | – | – |
> 2 years versus < 2 years | 0.68 (0.34–1.37) | 0.28 | – | – |
Biomarkers | ||||
Blood eosinophil count \(\ge\) 298 versus < 298 | 8.87 (4.73–16.62) | < 0.001 | 8.79 (4.44–17.4) | < 0.001 |
NLR \(\ge\) 2.52 versus < 2.52 | 3.04 (1.72–5.35) | < 0.001 | 2.13 (1.09–4.14) | 0.027 |