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Table 3 Univariate and multivariate analyses to determine predictors of hospitalization in pediatric patients with asthma exacerbation

From: Can eosinophilia and neutrophil–lymphocyte ratio predict hospitalization in asthma exacerbation?

 

Univariate analysis

Multivariate analysis

Crude OR (95% CI)

P

Adjusted OR (95% CI)

P

Gender, female

1.87 (1.07–3.28)

0.029

1.96 (0.98–3.91)

0.057

Not using an asthma action plan

2.15 (1.2–3.84)

0.01

2.22 (1.09–4.49)

0.027

Atopy status

1.13 (0.63–2.02)

0.674

Cause of the exacerbation

 Infection versus non-infectious cause

1.53 (0.85–2.73)

0.153

1.65 (0.81–3.36)

0.169

 Allergen versus non-allergenic cause

0.58 (0.19–1.72)

0.323

 Non-adherence to prescribed therapy versus adherence

0.87 (0.45–1.68)

0.671

Duration of asthma

 < 1 year versus > 1 year

0.69 (0.37–1.27)

0.233

 1–2 years versus < 1 year and > 2 years

1.04 (0.57–1.87)

0.904

 > 2 years versus < 2 years

0.68 (0.34–1.37)

0.28

Biomarkers

 Blood eosinophil count \(\ge\) 298 versus < 298

8.87 (4.73–16.62)

< 0.001

8.79 (4.44–17.4)

< 0.001

 NLR \(\ge\) 2.52 versus < 2.52

3.04 (1.72–5.35)

< 0.001

2.13 (1.09–4.14)

0.027