Table 5 Serum levels of serological biomarkers in patients with anaphylaxis and non-anaphylactic immediate hypersensitivity to cefaclor
Anaphylaxis (n = 281) Mean ± SD, (n) | Non-anaphylaxis (n = 178) Mean ± SD, (n) | P-value | |
|---|---|---|---|
Total IgE, kU/L | 345 ± 509.88 (166) | 331.28 ± 522.19 (64) | 0.851 |
Tryptase, µg/L | 16.36 ± 25.37 (62) | 4.63 ± 2.75 (5) | 0.309 |
Specific IgE to cefaclor, kU/L High cefaclor IgE (> 0.35 kU/L) | 6.45 ± 15.62 (236) 153/236 (64.8%) | 1.73 ± 4.69 (97) 28/97 (28.9%) | 0.004 < 0.001 |
Specific IgE to amoxicilloyl, kU/L | 0.12 ± 0.19 (131) | 0.09 ± 0.09 (52) | 0.302 |
Specific IgE to ampicilloyl, kU/L | 0.22 ± 0.63 (127) | 0.09 ± 0.10 (51) | 0.155 |
Specific IgE to penicilloyl G, kU/L | 0.17 ± 0.91 (126) | 0.54 ± 3.18 (49) | 0.237 |
Specific IgE to penicilloyl V, kU/L | 0.38 ± 1.74 (122) | 1.09 ± 6.86 (47) | 0.285 |