Table 1 Medication washout periods
Medication | Washout period |
|---|---|
Beta-blockers, alpha-adrenoceptor blockers | Not permitted |
Topical alpha-adrenergic agonists | 48Â h |
Short-Acting Antihistamines (e.g. Diphenhydramine) | *3Â days |
Anti-allergic eye drops (ocular antihistamines, decongestants and cromoglycates) | 5Â days |
Long-Acting Antihistamines (e.g. fexofenadine, loratadine, cetirizine)–note that H2 antagonists (e.g. Zantac, ranitidine) are not considered antihistamines for the purposes of this study | *5 days |
Anticholinergics | 7Â days |
Topical Corticosteroids (except 1% or less of hydrocortisone) | 7Â days |
Intranasal or inhaled corticosteroids (e.g. triamcinolone acetonide, fluticasone) | **14Â days |
Intranasal or inhaled cromolyn | 14Â days |
Leukotriene inhibitors | 14Â days |
Tricyclic Antidepressants and Monoamine oxidase inhibitors | 14Â days |
Systemic corticosteroids (oral) | 30Â days |
Depot corticosteroids | 60Â days |
Biologics | 6Â months |