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Fig. 2 | Allergy, Asthma & Clinical Immunology

Fig. 2

From: Taurine promotes the production of CD4+CD25+FOXP3+ Treg cells through regulating IL-35/STAT1 pathway in a mouse allergic rhinitis model

Fig. 2

IL-35 antibody partly disrupted the function of taurine in mouse AR model. A Taurine treatment reduced the sneezing number of model mouse. ***p  <  0.001 vs Control; ###p  <  0.001 vs Model; !p  <  0.05 vs Model  +  3% T. T: Taurine. B The concentrations of IL-4, IL-5, IL-13 and IL-35 were examined in different group as indicated. **p  <  0.01 vs Control, ***p  <  0.001 vs Control; ###p  <  0.001 vs Model; !p  <  0.05 vs Model  +  3% T. C Taurine treatment alleviated the AR-induced injury in mouse. D The percentage of CD4  +  CD25  +  Foxp3  +  Treg cells was increased in model group with Taurine treatment. ***p  <  0.001 vs Control; ##p  <  0.01 vs Model; !p  <  0.05 vs Model  +  3% T. E Western blot was used to examine the protein contents of IL-35, Foxp3, STAT1 and p-STAT1 in different nasal mucosal tissues as indicated. **p  <  0.01 vs Control, ***p  <  0.001 vs Control; ###p  <  0.001 vs Model; !!!p  <  0.001 vs Model  +  3% T

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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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