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Table 4 Summary of gene–gene interactions for CBIgE elevation by GMDR analysis

From: Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children

Interacting SNPs

TBA

P value

IL13 rs20541 × ADRB2 rs1042713

0.5621

1.07 × 10–2

IL13 rs1800925 × IL4 rs2243250 × ADRB2 rs1042713

0.5591

7.77 × 10–3

IL13 rs20541 × IL13 rs1800925 × IL4 rs2243250 × ADRB2 rs1042713

0.5805

9.03 × 10–4

IL13 rs20541 × IL13 rs1800925 × IL13 rs1295686 × IL4 rs2243250 × ADRB2 rs1042713

0.5724

1.53 × 10–3

  1. CBIgE cord blood IgE, GMDR generalized multifactor dimensionality reduction, SNP single-nucleotide polymorphism, TBA Testing balanced accuracy
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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