Interstitial lung disease occurring shortly after tocilizumab infusion in a patient with polyarticular juvenile idiopathic arthritis: a case report

Table 1 Laboratory test results 5 days after the first tocilizumab administration

Hematology		Biochemistry		Immunology
WBCs	5.76 × 10⁹/L	CRP	0.1 mg/L	ANA	× 40 (homo)
Neutrophils	73.0%	TP	71 g/L	IgA	1970 mg/L
Eosinophils	1.0%	Alb	36 g/L	IgM	1370 mg/L
Basophils	1.0%	Urea	3.6 mmol/L	IgG	21,490 mg/L
Lymphocytes	21.0%	Cr	31 µmol/L	β-D glucan	−
Monocytes	4.0%	T-Bil	14 µmol/L	Procalcitonin	−
RBCs	2390 × 10⁹/L	AST	38 IU/L	T-SPOT	−
Hb	59 g/L	ALT	19 IU/L	CMV Ag (C10, 11)	(0,0)
Hct	19.9%	ALP	246 IU/L	Anti-Trichosporon asahii antibody	−
Platelets	231 × 10⁹/L	LDH	612 IU/L	Blood gas analysis (nasal oxygen 3 L/min)
MCV	83.3 fL	γ-GTP	14 IU/L	pH	7.429
MCH	24.7 pg	Na	136 mmol/L	PaO₂	71.1 mmHg
MCHC	29.6%	K	4.2 mmol/L	PaCO₂	33.1 mmHg
Ret	10.1%	Cl	105 mmol/L	HCO₃	21.4 mmol/L
		KL-6	1820 U/mL	BE	-2.6 mmol/L
		Ferritin	593.7 µg/L

WBC white blood cell, RBC red blood cell, Hb hemoglobin, Hct hematocrit, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration, Ret reticulocytes, CRP C-reactive protein, TP total protein, Alb albumin, Cr creatinine, T-Bil total bilirubin, AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, LDH lactate dehydrogenase, γ-GTP gamma glutamyl transferase, KL-6 Krebs von den Lungen-6, ANA anti-neutrophil antibody, T-SPOT T-SPOT®.TB test for Mycobacterium tuberculosis, CMV Ag cytomegalovirus antigen, BE base excess

ISSN: 1710-1492