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Table 1 Characteristics of included studies (part 1)

From: Atopic dermatitis and risk of autoimmune diseases: a systematic review and meta-analysis

Study Location Study design Assessment of AD Assessment of AID Cases (AD) Control
Total, n Age (Mean ± SD), y Female (%) Total, n Age (Mean ± SD), y Female (%)
Shalom et al. [17] 2020 Israel Cross-sectional Dermatologist Gastroenterologist 116,816 21.4 ± 20.1 61,892 (53.0) 116,812 21.4 ± 20.1 61,889 (53)
Narla et al. [20] 2018 USA Cross-sectional ICD-9 ICD-9 87,053,155 NA NA 87,033,669 NA NA
Egeberg et al. [11] 2017 Denmark Case–control ICD-10 ICD-10 7,937 34.3 ± 14.1 4,901 (61.8) 79,370 34.3 ± 14.1 49,010 (61.8)
Andersen et al. [12] 2016 Denmark Case–control ICD-10 ICD-10 8,112 42.4 ± 15.2 4,982 (61.4) 40,560 42.4 ± 15.2 24,910 (61.4)
Radtke et al. [10] 2016 Germany Case–control ICD-10 ICD-10 48,140 NA NA 1,301,531 NA NA
Augustin et al. [14] 2015 Germany Case–control ICD-10 ICD-10 30,354 NA NA 262,827 NA NA
Wu et al. [18] 2014 China Taiwan Case–control ICD-9 ICD-9 41,950 34.7 ± 23.8 22,775 (54.3) 167,800 34.7 ± 23.8 91,100 (54.29)
Soh et al. [16] 2020 Korea Cohort ICD-10 ICD-10 1,557,435 NA NA 8,366,086 NA 3,618,584 (43.2)
Wei et al. [15] 2020 China Taiwan Cohort ICD-9 ICD-9 40,307 20.6 (8.8–37.9) 22,546 (55.9) 161,228 20.6 (8.8–37.9) 90,184 (55.9)
Krishna et al. [9] 2019 UK Cohort Medical records Medical records 1,393,570 29.8 (25.3) 754,293 (54.1) 2,170,618 32.7 (25.5) 1,167,859 (53.8)
Drucker et al. [21] 2017 USA Cohort Self-reported Self-reported 9,234 54.4 (4.6) 9,234 (100) 78,172 54.5 (4.7) 78,172 (100)
Schmitt et al. [13] 2016 UK Cohort ICD-10 ICD-10 49,847 NA 29,231 (58.6) 605,968 NA 295,510 (48.8)
Lai et al. [22] 2015 Canada Cohort ICD-9 ICD-9 18,907 NA NA 170,238 46.6 ± 17.4 92,736 (54.5)
Wei et al. [19] 2014 China Taiwan Cohort ICD-9 ICD-9 192,357 3.2 ± 0.04 89,749 (46.7) 769,428 3.3 ± 0.04 358,995 (46.7)
  1. ICD international classification of diseases, AD atopic dermatitis, AID autoimmune diseases, NA not available