Table 1 Summary of the patient’s clinical manifestations
Clinical presentations | Age of presentation | Paraclinical findings | |
|---|---|---|---|
Allergy | Food allergy presenting with chronic and bloody diarrhea | Starting at 12 months disappearing at 24 months | Stool exam WBC: many (NR: 0–5/HPF) RBC: 30–35 (NR: 0–5/HPF) Stool α1 antitrypsin: 125 mg/dl (NR: < 54 mg/dl) calprotectin: 850 mcg/g (NR: < 50 mcg/g) SPTƗ: significantly positive for pistachio, egg white, wheat flour, ray flour, and milk tTG IgG±: 1.3 IU/ml (Negative range: < 10 IU/ml) anti-gliadin IgG:10.4 U/ml (Negative range: < 12 IU/ml) |
Infectious | Frequent upper and lower respiratory tract infections Recurrent otitis media Cervical lymphadenopathies Herpetic lesions on the hand fingers | emerging at 7 months continuing until a few months after starting of the IVIG therapy | Sputum sample PCR$: negative for EBV, HIV, meningococcus, pneumococcus, and influenza virus positive for haemophilus influenza on one occasion Anti-toxoplasma IgG and IgM antibodies: negative anti-cytomegalovirus (CMV) IgM antibody: negative |