Fig. 6
From: MiRNA-221-5p suppressed the Th17/Treg ratio in asthma via RORγt/Foxp3 by targeting SOCS1
The inhibition of SOCS1 reduced the effects of anti-miRNA-221-5p on Th17/Treg Ratio in asthma. SOCS1, RORγt and Foxp3 protein expression by statistical analysis (A–C) and western blotting analysis (D), IL-6 (E), IL-17 (F), IL-21 (G), IL-22 (H), IL-10 (I), IL-35 (J) and TGF-β (K) levels. Negative, negative mimics group; anti-221-5p, down-regulation of miRNA-221-5p group; si-SOCS1, si-SOCS1 and down-regulation of miRNA-221-5p group. **p < 0.01 versus negative mimics group, ##p < 0.01 versus down-regulation of miRNA-221-5p group