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Table 6 Correlation of various genetic variants with IL-13 levels of cases and controls

From: Atopy in Kashmir-validation from a case control study with respect to IgE and Interleukin genes

Overall genotype/

Cases

OR (95%CI)

P value

IL-4 levels

Number (n)

Un (%)

D n (%)

 

n = 528

00 (00.0)

528 (100.0)

  

IL-4 RA (A148G)

   

0.2 (0.01–4.1)

0.4

 AA

108 (20.4)

00

108

 AG + GG

420 (79.6)

00

420

IL-4RA (A1902G)

   

0.2 (0.01–3.8)

0.3

 AA

102 (19.3)

00

102

 AG + GG

426 (70.7)

00

426

IL-4 70 bp VNTR

   

0.2 (0.01–3.4)

0.3

 2 repeats

93 (17.6)

00

93

 2/3 repeats

435 (72.4)

00

435

IL-13 (C1055T)

   

0.6 (0.04–10.3)

0.6

 CC

207 (39.2)

00

207

 CT + TT

321 (60.8)

00

321

IL-13 (A1512C)

   

0.2 (0.01–3.7)

0.3

 AA

99 (18.7)

00

99

 AC + CC

429 (71.3)

00

429

STAT-6 (G2964A)

     

 GG

156 (29.5)

00

156

0.4 (0.02–6.7)

0.5

 GA + AA

372 (70.5)

00

372

  
  1. IL Interleukin, U undetectable, D detectable
  2. 0.7 pg/ml is the minimum value below which the interleukin levels (IL-4) were treated as undetectable
  3. 1.5 pg/ml is the minimum value below which the interleukin levels (IL-13) were treated as undetectable