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Table 1 Evaluation of the AD-like dermatitis scoring system

From: The STAT6 inhibitor AS1517499 reduces the risk of asthma in mice with 2,4-dinitrochlorobenzene-induced atopic dermatitis by blocking the STAT6 signaling pathway

Group

Number of mice

Score

VC

10

0

AD

10

16.2 ± 1.38*

COTR

10

15.8 ± 1.5*

AS

10

9.2 ± 1.73**

  1. The total score involved the sum of seven clinical items: hemorrhagic erythema, scars, scratches, erosion, dryness, exfoliation, and swelling
  2. The degree of each symptom was scored 0 (none), 1 (mild), 2 (moderate) or 3 (severe)
  3. Scoring was done twice a week
  4. The results are expressed as mean ± SD (n = 5)
  5. *P < 0.05 indicates significant difference between the AD group and vehicle control (VC) groups
  6. **P < 0.05 indicates significant difference between the AS and AD groups
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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