Quality of life parameters |
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1. High costs |
2. Presence of comorbidities |
3. Unpredictability of symptoms |
4. Impact on the family |
5. Interference with health-related quality of life |
6. School and work decreased performance |
7. Resistance to treatment |
8. Long disease duration |
9. Effects of concomitant angioedema (body deformation, asphyxia) |
10. Interference with sexual function |
11. Interference with social interactions |