A new way forward? Examining the potential of quantitative analysis of IgE datasets

Table 3 Comparison of specific IgE for given food and aeroallergens for young patients between 0 and 20 years tested in 2003 to 2010 versus 2011 to 2020

Aeroallergens	Birch pollen			Mugwort pollen			Timothy grass pollen			Dermatophagoides pteronyssinus			Cat epithelia
Year of test	n	mean with 95% CI	p / Sig	n	mean with 95% CI	p/Sig	n	mean with 95% CI	p/Sig. /dif	n	mean with 95% CI	p/Sig./dif	n	mean with 95% CI	p/Sig
2003–2010	386	14.20 ± 14.90	0.346 n.s	394	2.03 ± 8.66	0.203 n.s	432	18.83 ± 14.02	0.001**	417	12.17 ± 14.64	0.013*	386	3.69 ± 12.59	0.89 n.s
2011–2020	358	12.28 ± 15.01		322	1.44 ± 9.81		431	12.16 ± 14.82	−6.68 ± 3.85	430	8.10 ± 14.76	–4.07 ± 3.21	334	3.83 ± 15.12

Significant results shown as the mean difference within the 95% confidence intervals are marked in bold

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