Table 4 Description of allergen specific antibodies, before, 1, 2 and 3 years of allergen immunotherapy
Allergen antibodies (kUA/L, g/L) | Base mean (95% CI) | One year mean (95% CI) | Two years mean (95% CI) | Three years mean (95% CI) | p value † |
|---|---|---|---|---|---|
IgE birch, | 151.0 (113.5–188.6) n = 134 | 99.4 (77.9–120.8) n = 117 | 88.1 (66.2–110.0) n = 104 | 76.8 (57.0–96.7) n = 109 | < 0.001 |
IgG4 birch | 2.2 (0.9–3.4) n = 93 | 8.8 (6.9–10.7) n = 85 | 15.0 (12.2–17.9) n = 75 | 17.6 (14.8–20.5) n = 70 | < 0.001 |
IgE grass | 37.8 (4.9–70.8) n = 22 | 22.0 (8.8–35.2) n = 18 | 20.8 (7.5–34.2) n = 18 | 16.8 (5.9–27.6) n = 18 | 0.070 |
IgG4 grass | 0.5 (0.1–0.9) n = 21 | 12.9 (8.1–17.7) n = 17 | 15.3 (8.5–22.2) n = 17 | 14.3 (7.5–21.1) n = 17 | < 0.001 |