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Table 2 SNOT-22 outcomes

From: Clinical outcomes of dupilumab therapy in chronic rhinosinusitis with nasal polyps in a Canadian tertiary care rhinology practice

 

Baseline SNOT-22

SNOT-22 1-month post-dupilumab

Change in SNOT-22 1-month post-dupilumab

SNOT-22 3 months post-dupilumab

Change in SNOT-22 3-months post-dupilumab

SNOT-22 6 months post-dupilumab

Change in SNOT-22 6-months post-dupilumab

SNOT-22 12 months post-dupilumab

Change in SNOT-22 12-months post-dupilumab

Total cohort (Mean ± SD)

60.6 ± 18.8

56.8 ± 37.4

− 8.8 ± 10.5

40.4 ± 16.8

− 26.5 ± 14.0

26.1 ± 22.0

− 42.8 ± 24.6

26.1 ± 17.9

− 33.8 ± 26.3

AERD

(Mean ± SD)

56.5 ± 14.4

24 ± 33.9

− 5.5 ± 7.8

31.3 ± 22.2

− 28.3 ± 16.2

27.4 ± 21.8

− 40.3 ± 29.0

15.2 ± 17.8

− 46.0 ± 18.9

  1. All values are reported as means ± standard deviations
  2. SNOT-22 Sinonasal outcome test, SD standard deviation, AERD aspirin exacerbated respiratory disease