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Table 3 Clinical features of HAE patients

From: National survey on clinical and genetic characteristics of patients with hereditary angioedema in Latvia

Clinical features

Findings

Attacks per year since the diagnosis of HAE (n = 10)

 1–5

4

 6–11

2

 12–24

0

 > 24

4

Frequency of attacks in the last 12 monthsa (n = 9)

 Mild

4

 Moderate

1

 Severe

4

Swelling location (n = 10)

 Skin

10

 Lips

9

 Tongue

8

 Abdomen

8

 Larynx

8

 Urogenital area

3

Prodrome (n = 9)

 Tiredness

8

 Paraesthesia/pain

8

 Abdominal pain

8

Nausea

3

Erythema marginatum

2

Trigger factors (n = 6)

 Stress

4

 Trauma

2

 Surgical/dental manipulations

2

 Infection

1

 Menstruation

1

  1. aSevere—if the patient had experienced 12 or more attacks during the last 12 months, moderate—4 − 11 attacks, mild—1 − 3 attacks, and asymptomatic—no attacks