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Table 2 eConsults coded by question posed to specialist

From: Utility of eConsults for COVID-19 vaccine-related concerns in Ontario: a cross-sectional analysis

Reaction

Total (%)

Pre-existing diagnosis of allergy to non-COVID-19 vaccine

205 (41.1)

Potential IgE-mediated allergic reactions

Other vaccines

62 (12.4)

Medications

47 (9.4)

Polyethylene glycol

14 (2.8)

Food

14 (2.8)

Radiocontrast media

14 (2.8)

Stinging insect

1 (0.2)

Other

9 (1.8)

Non-IGE-mediated allergic reaction

Type IV (Delayed) non-polyethylene glycol allergen

5 (1.0)

Type IV (Delayed) to polyethylene glycol

0 (0.0)

Other

4 (0.8)

Non-allergic reactions

Other vaccines

35 (7.0)

Pre-existing medical comorbidities

74 (14.8)

Immune-related

 

Autoimmune disease

9 (1.8)

Secondary immunodeficiency

9 (1.8)

Primary immunodeficiency

3 (0.6)

Immunosuppressive therapy

2 (0.4)

Pregnancy

1 (0.2)

Non-immune-related

 

Thromboembolic disease or hypercoagulability

17 (3.4)

Cutaneous conditions

6 (1.2)

Cancers

0 (0.0)

Other

27 (5.4)

Adverse Reaction to Dose 1 of COVID Vaccine

180 (36.1)

Potential IgE-mediated allergic reactions

Subjective or objective immediate angioedema, dyspnea, rashes, GI symptoms, or pre-syncope/syncope

34 (6.8)

Non-IgE-mediated allergic reaction

Delayed skin rashes

54 (10.8)

Other

10 (2.0)

Non-Allergic reaction

Neurological (Numbness, Tingling)

27 (5.4)

Delayed Flu-like Symptoms

11 (2.2)

Myocarditis

3 (0.6)

Other

38 (7.6)

Questions Regarding Potential Vaccine Exemption

15 (3.0)

Pediatric Age-Related Concerns

1 (0.2)

General Anxiety about COVID-19 Vaccination

7 (1.4)

Mixing of COVID-19 Vaccines

0 (0.0)

Administration-Related Concerns

9 (1.8)

Other

8 (1.6)

TOTAL

499

  1. IgE = Immunoglobulin E, COVID-19 = coronavirus disease 2019 cause by the novel coronavirus SARS-CoV-2, GI = gastrointestinal