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Table 4 Mean laboratory values of immunoglobulins in the 10 years before the censoring date

From: Development of a primary care screening algorithm for the early detection of patients at risk of primary antibody deficiency

 

General population (N = 58,223)

Upper RTI (N = 13,133)

COPD/asthma (N = 4427)

IBD (N = 403)

Malignancy (N = 1526)

Immunodef. pre-diagnosis (N = 26)

PAD pre-diagnosis (N = 30)

IgA (g/L)

2.01 (1.06) (n = 541)

2.09 (1.11) (n = 240)

2.32 (1.44) (n = 63)

2.51 (1.00) (n = 10)

2.31 (0.98) (n = 24)

–

–

IgG1 (g/L)

3.8 (0) (n = 1)

3.8 (0) (n = 1)

–

–

–

–

–

IgG2 (g/L)

3.34 (0) (n = 1)

3.34 (0) (n = 1)

–

–

–

–

–

IgG3 (g/L)

0.67 (0) (n = 1)

0.67 (0) (n = 1)

–

–

–

–

–

IgG4 (g/L)

0.06 (0) (n = 1)

0.06 (0) (n = 1)

–

–

–

–

–

IgG total (g/L)

10.6 (2.87) (n = 65)

11.28 (2.09) (n = 34)

11.08 (1.55) (n = 11)

–

11.37 (1.96) (n = 9)

–

–

IgM (g/L)

2.63 (4.73) (n = 67)

1.79 (1.97) (n = 34)

2.44 (9.53) (n = 11)

–

2.49 (6.42) (n = 10)

–

–

Calculated globulin (g/L)

26.34 (12.12) (n = 221)

30.66 (9.25) (n = 89)

26.79 (13.53) (n = 38)

33.70 (0.71) (n = 3)

28.61 (15.83) (n = 23)

–

–

  1. Values are shown as mean (standard deviation). EHR data from the 10 years before the censoring date. A ‘–’ indicates that this laboratory value has not been requested for this patient group
  2. COPD chronic obstructive pulmonary disease, IBD inflammatory bowel disease, EHR electronic health record, Ig immunoglobulin, immunodef. immunodeficiency patients from primary care, PAD primary antibody deficiencies, RTI respiratory tract infection