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Table 3 LTP treatment prescriptions, overall and by country

From: A multicenter chart review of patient characteristics, treatment, and outcomes in hereditary angioedema: unmet need for more effective long-term prophylaxis

n (%)

Overall (N = 225)

US (n = 56)

Canada (n = 51)

Germany (n = 45)

Australia (n = 35)

UK (n = 24)

Italy (n = 14)

Patients with any LTP usea

121 (53.8)

34 (60.7)

33 (64.7)

13 (28.9)

19 (54.3)

21 (87.5)

1 (7.1)

Plasma-derived C1-INH

 Berinert®

31 (25.6)

2 (5.9)

17 (51.5)

4 (30.8)

7 (36.8)

1 (4.8)

0

  Intravenous

25 (20.7)

2 (5.9)

14 (42.4)

1 (7.7)

7 (36.8)

1 (4.8)

0

  Subcutaneousb

8 (6.6)

0

4 (12.1)

4 (30.8)

0

0

0

 Cinryze®

36 (29.8)

21 (61.8)

6 (18.2)

7 (53.8)

0

2 (9.5)

0

 Haegarda®

9 (7.4)

9 (26.5)

0

0

0

0

0

Androgen therapy

 Danazol

65 (53.7)

15 (44.1)

19 (57.6)

2 (15.4)

11 (57.9)

18 (85.7)

0

 Stanozolol

7 (5.8)

3 (8.8)

1 (3.0)

0

3 (15.8)

0

0

 Oxandrolone

3 (2.5)

0

0

0

1 (5.3)

2 (9.5)

0

Tranexamic acid

15 (12.4)

0

5 (15.2)

0

7 (36.8)

2 (9.5)

1 (100.0)

Ruconest®

1 (0.8)

1 (2.9)

0

0

0

0

0

Lanadelumab

11 (9.1)

7 (20.6)

0

4 (30.8)

0

0

0

  1. Values are n (%)
  2. C1-INH C1 inhibitor, HAE hereditary angioedema, LTP long-term prophylaxis
  3. aPatients may have received ≥ 1 treatment prescription during follow-up
  4. bBerinert® is approved for intravenous administration to treat acute attacks of HAE in pediatric and adult patients. Subcutaneous administration for on-demand treatment of attacks is unapproved