Table 1 (abstract P-49) Inheritance pattern of HAE-C1-INH with SERPING1 mutation
From: 13th C1-inhibitor deficiency and angioedema workshop—2023
Total offspring | Total male offspring | Total female offspring | ||||||
|---|---|---|---|---|---|---|---|---|
Mutant | Wild type | P value | mutant | Wild type | P | mutant | Wild type | p |
172 (49.1%) | 178 (50.8%) | 0.6 | 90 (45.4%) | 108 (54.5%) | 0.07 | 82 (53.9%) | 70 (46%) | 0.1 |
Paternal Inheritance | Maternal Inheritance | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Male offspring | Female offspring | Male offspring | Female offspring | ||||||||
Mutant | Wild type | p | Mutant | Wild type | p | Mutant | Wild type | p | Mutant | Wild type | p |
41 (41.8%) | 57 (58.1%) | 0.02 | 39 (52.7%) | 35 (47.3%) | 0.5 | 49 (49%) | 51 (51%) | 0.7 | 43 (55.1%) | 35 (44.8%) | 0.2 |