Association between interleukin-6-174G/C gene polymorphism and asthma severity: exploring the role of total serum IgE, blood eosinophils, and FeNO as markers of type 2 inflammation

Table 3 Type 2 inflammatory markers in correlation with dominant model of IL-6 gene (-174G/C) polymorphism

Factors	GG (n = 45)		CC + CG (n = 169)		p
	Mean/median	SD/IQR	Mean/median	SD/IQR
Age (Years)	40.1	18.7	47.5	14.8	0.01^a
Female-sex	33	73.33	113	66.86	0.41^c
BMI	30.96	7.27	30.86	6.1	0.93^c
IgE	123	(36–400)	191.1	(69–522)	0.04^b
BE	0.2	(0.1–0.5)	0.3	(0.2–0.7)	0.03^b
FeNO	13	(4–22)	17	(9–33)	0.04^b

Numerical data represented as mean and standard deviation or median and inter quartile range, and categorical data as number and percentage
N number, SD standard deviation, IQR Inter quartile range, BMI body mass index, IgE immunoglobulin E, FeNO Fractional expired nitric oxide
^aIndependent t-test
^bMann Whitney test
^cChi square test
Text in Bold represents a significant p value; p < 0.05

ISSN: 1710-1492