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Table 4 Predictors of severe asthma

From: Association between interleukin-6-174G/C gene polymorphism and asthma severity: exploring the role of total serum IgE, blood eosinophils, and FeNO as markers of type 2 inflammation

Factors

OR

95% CI

p

Un-adjusted model

 Dominant (CC + GC)

4.40

(2.1209, 9.1283)

 < 0.001

Adjusted model

 Age

1.13

(1.0727, 1.1999)

 < 0.001

 Sex (male)

1.32

(0.2986, 5.8428)

0.71

 Asthma onset (Childhood)

19.19

(3.3314, 110.5572)

 < 0.001

 AR

5.00

(1.2885, 19.4386)

0.01

 NP

32.29

(6.2848, 165.8691)

 < 0.001

 BMI

1.11

(1.0051, 1.2214)

0.04

 IgE

1.00

(0.9999, 1.0033)

0.05

 FeNO

1.04

(1.0168, 1.0729)

0.001

 Dominant (CC + GC)

8.12

(1.4630, 45.0226)

0.01

  1. The test of fitness: Hosmer–Lemeshow test, X2 = 7.77, p = 0.45, the test of significance: Logistic regression models with backward elimination methods
  2. OR odd ratio, CI Confidence interval, BMI body mass index, IgE immunoglobulin E, FeNO Fractional expired nitric oxide, DM diabetes mellitus, AR allergic rhinitis, NP nasal polyp
  3. Text in Bold represents a significant p value; p < 0.05
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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