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  1. Content type: Research

    Allergic rhinitis affects 10–30 % of the global population and this number is likely to increase in the forthcoming years. Moreover, it commonly co-exists with allergic asthma as a chronic allergic respiratory...

    Authors: Agata Schramm, Barbara Jasiewicz-Honkisz, Grzegorz Osmenda, Grzegorz Wilk, Mateusz Siedlinski, Agnieszka Sagan, Pawel T. Matusik, Joanna Maciag, Tomasz Sliwa, Marta Czesnikiewicz-Guzik and Tomasz P. Mikolajczyk

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:55

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  2. Content type: Research

    Immune responses in allergic diseases begin with allergen sensitization, which usually occurs in childhood. Allergen sensitization involves a complex interplay of genetic and environmental factors, and sensiti...

    Authors: Evelyn Xiu Ling Loo, Jordan Zheng Ting Sim, Anne Goh, Oon Hoe Teoh, Yiong Huak Chan, Seang Mei Saw, Kenneth Kwek, Peter D. Gluckman, Keith M. Godfrey, Hugo Van Bever, Yap Seng Chong, Bee Wah Lee, Michael S. Kramer and Lynette Pei-chi Shek

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:56

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  3. Content type: Research

    Cow’s milk allergy is one of the most common food allergies affecting young children. A subset of milk-allergic individuals can eat baked milk without allergic symptoms which is beneficial in terms of prognost...

    Authors: Allison Kwan, Maria Asper, Sasson Lavi, Elana Lavine, David Hummel and Julia E. Upton

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:54

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  4. Content type: Research

    To improve care and control for patients with adult-onset asthma, a better understanding of determinants of their risk and outcomes is important. We investigated how associations between asthma, asthma control...

    Authors: Corinna Koebnick, Heidi Fischer, Matthew F. Daley, Assiamira Ferrara, Michael A. Horberg, Beth Waitzfelder, Deborah Rohm Young and Michael K. Gould

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:50

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  5. Content type: Review

    Exposure to traffic-related air pollution (TRAP) has been implicated in asthma development, persistence, and exacerbation. This exposure is highly significant as large segments of the global population resides...

    Authors: Hong Ji, Jocelyn M. Biagini Myers, Eric B. Brandt, Cole Brokamp, Patrick H. Ryan and Gurjit K. Khurana Hershey

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:51

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  6. Content type: Review

    Atopic dermatitis (AD) is a chronic inflammatory disease caused by the complex interaction of genetic, immune and environmental factors. There have many recent discoveries involving the genetic and epigenetic ...

    Authors: Lianghua Bin and Donald Y. M. Leung

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:52

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  7. Content type: Research

    The Environmental Exposure Unit (EEU) in Kingston, Ontario, Canada is a controlled allergen challenge facility (CACF) that has been previously clinically validated for the use of ragweed and grass pollen in cl...

    Authors: Anne K. Ellis, Mena Soliman, Lisa M. Steacy, Daniel E. Adams, Barnaby Hobsbawn and Terry J. B. Walker

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:53

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  8. Content type: Research

    Epidemiological studies have implicated Asian sand dust (ASD) in the increased prevalence of respiratory disorders, including asthma. It has been observed that fungal elements such as β-glucan can be adsorbed ...

    Authors: Kaori Sadakane, Takamichi Ichinose, Masataka Nishikawa, Hirohisa Takano and Takayuki Shibamoto

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:48

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  9. Content type: Research

    Adrenal suppression (AS), a glucocorticoid (GC) side effect associated with significant morbidity, is well described related to inhaled corticosteroid therapy for asthma. Swallowed topical glucocorticoid thera...

    Authors: Alexandra Ahmet, Eric I. Benchimol, Ellen B. Goldbloom and Janice L. Barkey

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:49

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  10. Content type: Research

    In patients with asthma, the fungus Aspergillus fumigatus can cause allergic bronchopulmonary aspergillosis (ABPA). Familial ABPA is reported, and some genetic factors have been associated with the disease, howev...

    Authors: Nicola L. D. Overton, David W. Denning, Paul Bowyer and Angela Simpson

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:47

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  11. Content type: Case Report

    Adult onset food allergy is a rare, but increasingly recognized phenomenon. Mast cell activation syndromes present an ongoing diagnostic and classification challenge. The combination of the two has been rarely...

    Authors: Colin Barber and Chrystyna Kalicinsky

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:46

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  12. Content type: Research

    Heterogeneity has been noted in the selection and reporting of disease-specific, pediatric outcomes in randomized controlled trials (RCTs). The consequence is invalid results or difficulty comparing results ac...

    Authors: Tamar Rubin, Jacqueline Clayton, Denise Adams, Rabin Persad and Sunita Vohra

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:45

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  13. Content type: Research

    Several studies have reported that oral immunotherapy (OIT) is effective for children with cow’s milk (CM) allergy. These studies reported the efficacy of OIT in terms of desensitization, but did not describe ...

    Authors: Masaya Takahashi, Shoichiro Taniuchi, Kazuhiko Soejima, Yasuko Hatano, Sohsaku Yamanouchi and Kazuanri Kaneko

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:44

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    The Erratum to this article has been published in Allergy, Asthma & Clinical Immunology 2016 12:57

  14. Content type: Proceedings

    A1 Role of fibrocytes in allergic rhinitis

    Authors: Marie-Ève Côté, Marie-Ève Boulay, Sophie Plante, Jamila Chakir, Louis-Philippe Boulet, Hanan Ahmed, Maria-Beatriz Ospina, Kyriaki Sideri, Harissios Vliagoftis, Sara F. Johnson, Roberta L. Woodgate, Guilhem Cros, Pierre Teira, Sonia Cellot, Henrique Bittencourt, Helene Decaluwe…

    Citation: Allergy, Asthma & Clinical Immunology 2016 12(Suppl 1):22

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    This article is part of a Supplement: Volume 12 Supplement 1

  15. Content type: Research

    To assess the relationship between any systemic antibiotic prescription within the first year of life and the presence of an ICD-9-CM diagnosis code for food allergy (FA).

    Authors: Bryan L. Love, Joshua R. Mann, James W. Hardin, Z. Kevin Lu, Christina Cox and David J. Amrol

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:41

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  16. Content type: Research

    Allergic rhinitis (AR) is characterised by burdensome nasal and/or ocular symptoms. This inflammatory disease can be debilitating and thus result in considerable health-related and economic consequences.

    Authors: A. Roger, E. Arcalá Campillo, M. C. Torres, C. Millan, I. Jáuregui, E. Mohedano, S. Liñan, P. Verdu, N. Rubira, M. Santaolalla, P. González, A. Orovitg and E. Villarrubia

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:40

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  17. Content type: Research

    The prevalence of allergies and the incidence of cancer are both increasing worldwide. It has been hypothesized that atopy may affect the risk of some cancers.

    Authors: Renata Kozłowska, Andrzej Bożek and Jerzy Jarząb

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:39

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  18. Content type: Research

    Ara h2 sIgE serum levels improve the diagnostic accuracy for predicting peanut allergy, but the use of Ara h2 purified protein as a skin prick test (SPT), has not been substantially evaluated. The fraction of ...

    Authors: Elizabeth Percival, Rani Bhatia, Kahn Preece, Patrick McElduff, Mark McEvoy, Adam Collison and Joerg Mattes

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:35

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  19. Content type: Research

    Hypersensitivity reaction to certain allergens plays a role in the pathogenesis of inflammatory bowel disease (IBD). This study aims to observe the effect of specific immunotherapy in a group of IBD patients.

    Authors: Min Cai, Lu Zeng, Lin-Jing Li, Li-Hua Mo, Rui-Di Xie, Bai-Sui Feng, Peng-Yuan Zheng, Zhi-Gang Liu, Zhan-Ju Liu and Ping-Chang Yang

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:37

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  20. Content type: Review

    Chronic rhinosinusitis (CRS) is a frequent chronic condition, which has origins in complex interactions between genetic, immunological and microbial factors. The role of auto-immunity in CRS remains unclear, a...

    Authors: Philippe Lefrançois, Hugo Chapdelaine, Benoît Côté and Martin Desrosiers

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:38

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  21. Content type: Research

    Only one previous study, via telephone call, on the prevalence of self-reported food allergies has been performed in Portugal, in a small sample of adults. The objective of this study was to determine the prev...

    Authors: Carlos Lozoya-Ibáñez, Sara Morgado-Nunes, Alexandra Rodrigues, Cláudia Lobo and Luis Taborda-Barata

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:36

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  22. Content type: Review

    Allergy immunotherapy (AIT) is acknowledged to produce beneficial mid- and long-term clinical and immunologic effects and increased quality of life in patients with allergic respiratory diseases (such as aller...

    Authors: Pascal Demoly, Giovanni Passalacqua, Oliver Pfaar, Joaquin Sastre and Ulrich Wahn

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:34

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  23. Content type: Research

    The incidence of allergic diseases is increasing gradually and is a global burden affecting the socio-economic quality of life. Identification of allergens is the first step towards paving the way for therapeu...

    Authors: Kavita Ghosal, Bodhisattwa Saha and Swati Gupta Bhattacharya

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:33

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  24. Content type: Review

    In Canada, intravenous immune globulin (IVIg) products are licensed for six disease indications, however it has been demonstrated that patients with a number of other conditions also benefit from IVIg. Here we...

    Authors: Stephen D. Betschel, Richard J. Warrington and Robert Schellenberg

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:32

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  25. Content type: Research

    Several null-mutations in the FLG gene that produce a decrease or absence of filaggrin in the skin and predispose to atopic dermatitis and ichthyosis vulgaris have been described. The relationship with asthma is ...

    Authors: José Luis Cubero, María Isidoro-García, Nieves Segura, David Benito Pescador, Catalina Sanz, Félix Lorente, Ignacio Dávila and Carlos Colás

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:31

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  26. Content type: Research

    Food allergy is a common clinical problem in adults. Given logistical barriers to conducting food challenges, the use of skin prick test (SPT) and specific IgE (sIgE) are important in establishing the diagnosi...

    Authors: Ling Ling, Maria B. Ospina, Kyriaki Sideri and Harissios Vliagoftis

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:30

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  27. Content type: Letter to the Editor

    Egg specific IgE levels are frequently used in combination with skin-prick tests to guide clinical decisions and to monitor egg allergy evolution in children. We compared both Immulite and ImmunoCAP egg specif...

    Authors: François Graham, Philippe Bégin, Louis Paradis, Jonathan Lacombe-Barrios, Jean Paradis and Anne Des Roches

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:29

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  28. Content type: Review

    Eosinophilia is not an uncommon clinical finding. However, diagnosis of its cause can be a dilemma once common culprits, namely infection, allergy and reactive causes are excluded. Primary immunodeficiency dis...

    Authors: Behdad Navabi and Julia Elizabeth Mainwaring Upton

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:27

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  29. Content type: Research

    Scratching in infants is considered to be related to early development of eczema. Little is known about the effects of maternal immune markers on scratching among infants. The objective is to compare the risks...

    Authors: Nelís Soto-Ramírez, Keith Boyd, Hongmei Zhang, Venugopal Gangur, Laura Goetzl and Wilfried Karmaus

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:25

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  30. Content type: Research

    Exposure to ammonium persulfate (AP) has been reported to be the main cause of occupational asthma in hairdressers. The aim of this study is to assess how long the asthmatic response to AP can be induced after...

    Authors: M. J. Cruz, M. Olle-Monge, J. A. Vanoirbeek, A. Assialioui, S. Gomez-Olles and X. Muñoz

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:26

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  31. Content type: Erratum

    Authors: Philippe Bégin, Lisa C. Winterroth, Tina Dominguez, Shruti P. Wilson, Liane Bacal, Anjuli Mehrotra, Bethany Kausch, Anthony Trela, Elisabeth Hoyte, Gerri O’Riordan, Scott Seki, Alanna Blakemore, Margie Woch, Robert G. Hamilton and Kari C. Nadeau

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:28

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    The original article was published in Allergy, Asthma & Clinical Immunology 2014 10:1

  32. Content type: Case report

    Although severe reactions to immunoglobulin preparations have been frequently reported, IgE antibodies against IgA are usually not investigated; and occur predominantly in previously sensitized patients. The p...

    Authors: Asal Gharib, Caroline Caperton and Sudhir Gupta

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:23

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  33. Content type: Letter to the Editor

    In this study, we assessed whether multisystem reactions to egg and extensively-heated (EH) egg during OFCs were associated with a history of multisystem reactions. Records of children, who underwent OFC to eg...

    Authors: Girish Vitalpur, Ann Esquivel, Kirsten M. Kloepfer, James E. Slaven and Frederick E. Leickly

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:21

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  34. Content type: Research

    Being one of the most common nasal diseases, chronic rhinosinusitis (CRS) is subdivided into CRS with nasal polyps (NP) and CRS without nasal polyps (CRSsNP). CRSsNP presents itself with a TH1 milieu and neutroph...

    Authors: Katrin König, Christine Klemens, Mareike Haack, Marion San Nicoló, Sven Becker, Matthias F. Kramer and Moritz Gröger

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:19

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  35. Content type: Review

    Allergic rhinitis is the most common form of allergy worldwide. The accuracy of skin testing for allergic rhinitis is still debated. Our primary objective was to evaluate the diagnostic accuracy of skin-prick ...

    Authors: Immaculate F. Nevis, Karen Binkley and Conrad Kabali

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:20

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  36. Content type: Research

    To evaluate total and specific E immunoglobulin (IgE) antibody concentrations in underage subjects with respiratory allergic diseases.

    Authors: Geusa Felipa de Barros Bezerra, Denise Maria Costa Haidar, Marcos Antonio Custódio Neto da Silva, Walbert Edson Muniz Filho, Ramon Moura dos Santos, Ivone Garros Rosa, Graça Maria de Castro Viana, Luís Zaror and Maria do Desterro Soares Brandão Nascimento

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:18

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  37. Content type: Letter to the Editor

    Overexpression and enhanced release of vascular endothelial growth factor (VEGF) have been detected in various types of allergic inflammation, including asthma.

    Authors: E. Koczy-Baron, A. Grzanka, J. Jochem, R. Gawlik and A. Kasperska-Zajac

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:17

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  38. Content type: Research

    Bisphenol A (BPA) is useful in many manufacturing processes and is also found in commonly used consumer products. Previous experimental studies have reported that perinatal exposure to BPA promotes the develop...

    Authors: Miao He, Takamichi Ichinose, Seiichi Yoshida, Hirohisa Takano, Masataka Nishikawa, Takayuki Shibamoto and Guifan Sun

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:16

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  39. Content type: Research

    Allergen immunotherapy (AIT) may be prescribed for patients with allergic rhinitis (AR) induced by house dust mites (HDM) whether asthma is present or not. Current guidelines provide insufficient support for t...

    Authors: Pascal Demoly, Anne Broué-Chabbert, François Wessel and Antoine Chartier

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:13

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  40. Content type: Research

    Several genome-wide association studies of primary biliary cirrhosis (PBC) in European and Japanese origins have shown significant association of dozens of genetic loci contributive to the susceptibility of PB...

    Authors: Ping Li, Guanting Lu, Li Wang, Ying Cui, Ziyan Wu, Si Chen, Jing Li, Xiaoting Wen, Haoze Zhang, Shijie Mu, Fengchun Zhang and Yongzhe Li

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:14

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  41. Content type: Research

    Immunological test systems for diagnostics of type I hypersensitivity involve the following types of antigens: whole allergen extracts, individual highly purified proteins and their recombinant analogues. The ...

    Authors: Olga Smoldovskaya, Guzel Feyzkhanova, Alla Arefieva, Sergei Voloshin, Olga Ivashkina, Yuriy Reznikov and Alla Rubina

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:9

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  42. Content type: Short report

    Asthma in the elderly is poorly understood as very few studies have included these patients. DNA methylation can affect the expression of asthma susceptibility genes. Methyl groups can be produced through a ch...

    Authors: Michele Columbo and Albert S. Rohr

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:15

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  43. Content type: Research

    Food allergy is the most common cause of anaphylaxis in children. Intramuscular delivery of epinephrine auto-injectors (EAI) is the standard of care for the treatment of anaphylaxis. We examined if children an...

    Authors: Sten Dreborg, Xia Wen, Laura Kim, Gina Tsai, Immaculate Nevis, Ryan Potts, Jack Chiu, Arunmozhi Dominic and Harold Kim

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:11

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    The Erratum to this article has been published in Allergy, Asthma & Clinical Immunology 2017 13:33

  44. Content type: Research

    T-cell receptor (TCR) repertoire development is an integral part of the adaptive immune response. T-cell activation requires recognition of appropriately processed antigens by the TCR. Development of a diverse...

    Authors: Gassem Gohal, Christine McCusker, Bruce Mazer, Reza Alizadehfar, Duncan Lejtenyi and Moshe Ben-shoshan

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:10

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  45. Content type: Research

    Several proangiogenic molecules have been implicated in the pathogenies of asthmatic inflammation and remodeling. The aim of the study was to compare the concentration of proangiogenic factors in the sera of a...

    Authors: Joanna S. Makowska, Małgorzata Cieślak, Marzanna Jarzębska, Anna Lewandowska-Polak and Marek L. Kowalski

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:8

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  46. Content type: Short report

    The prevalence of many phenotypes of food allergy is increasing. Specific gastrointestinal (GI) phenotype of food allergy (GI allergy) is also increasing but it is difficult to know the prevalence because of m...

    Authors: Paloma Poza-Guedes, Yvelise Barrios, Ruperto González-Pérez, Inmaculada Sánchez-Machín, Andres Franco and Víctor Matheu

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:7

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