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  1. Content type: Research

    Bisphenol A (BPA) is useful in many manufacturing processes and is also found in commonly used consumer products. Previous experimental studies have reported that perinatal exposure to BPA promotes the develop...

    Authors: Miao He, Takamichi Ichinose, Seiichi Yoshida, Hirohisa Takano, Masataka Nishikawa, Takayuki Shibamoto and Guifan Sun

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:16

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  2. Content type: Research

    Allergen immunotherapy (AIT) may be prescribed for patients with allergic rhinitis (AR) induced by house dust mites (HDM) whether asthma is present or not. Current guidelines provide insufficient support for t...

    Authors: Pascal Demoly, Anne Broué-Chabbert, François Wessel and Antoine Chartier

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:13

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  3. Content type: Research

    Several genome-wide association studies of primary biliary cirrhosis (PBC) in European and Japanese origins have shown significant association of dozens of genetic loci contributive to the susceptibility of PB...

    Authors: Ping Li, Guanting Lu, Li Wang, Ying Cui, Ziyan Wu, Si Chen, Jing Li, Xiaoting Wen, Haoze Zhang, Shijie Mu, Fengchun Zhang and Yongzhe Li

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:14

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  4. Content type: Research

    Immunological test systems for diagnostics of type I hypersensitivity involve the following types of antigens: whole allergen extracts, individual highly purified proteins and their recombinant analogues. The ...

    Authors: Olga Smoldovskaya, Guzel Feyzkhanova, Alla Arefieva, Sergei Voloshin, Olga Ivashkina, Yuriy Reznikov and Alla Rubina

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:9

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  5. Content type: Short report

    Asthma in the elderly is poorly understood as very few studies have included these patients. DNA methylation can affect the expression of asthma susceptibility genes. Methyl groups can be produced through a ch...

    Authors: Michele Columbo and Albert S. Rohr

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:15

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  6. Content type: Research

    Food allergy is the most common cause of anaphylaxis in children. Intramuscular delivery of epinephrine auto-injectors (EAI) is the standard of care for the treatment of anaphylaxis. We examined if children an...

    Authors: Sten Dreborg, Xia Wen, Laura Kim, Gina Tsai, Immaculate Nevis, Ryan Potts, Jack Chiu, Arunmozhi Dominic and Harold Kim

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:11

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    The Erratum to this article has been published in Allergy, Asthma & Clinical Immunology 2017 13:33

  7. Content type: Research

    T-cell receptor (TCR) repertoire development is an integral part of the adaptive immune response. T-cell activation requires recognition of appropriately processed antigens by the TCR. Development of a diverse...

    Authors: Gassem Gohal, Christine McCusker, Bruce Mazer, Reza Alizadehfar, Duncan Lejtenyi and Moshe Ben-shoshan

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:10

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  8. Content type: Research

    Several proangiogenic molecules have been implicated in the pathogenies of asthmatic inflammation and remodeling. The aim of the study was to compare the concentration of proangiogenic factors in the sera of a...

    Authors: Joanna S. Makowska, Małgorzata Cieślak, Marzanna Jarzębska, Anna Lewandowska-Polak and Marek L. Kowalski

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:8

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  9. Content type: Short report

    The prevalence of many phenotypes of food allergy is increasing. Specific gastrointestinal (GI) phenotype of food allergy (GI allergy) is also increasing but it is difficult to know the prevalence because of m...

    Authors: Paloma Poza-Guedes, Yvelise Barrios, Ruperto González-Pérez, Inmaculada Sánchez-Machín, Andres Franco and Víctor Matheu

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:7

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  10. Content type: Case report

    The immunological literature has been redefining clinical phenomena as hypotheses emerge regarding causal links between triggers, immunologic manifestations, and their specific inflammatory cascades. Of late, ...

    Authors: Matthew P. Cheng, Michael G. Kozoriz, Amir A. Ahmadi, John Kelsall, Katryn Paquette and Jake M. Onrot

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:6

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  11. Content type: Short report

    Accumulating evidence indicates a strong correlation between allergic disease and cardiovascular risks. In spite of this, the data concerning the association between allergic rhinitis (AR) and cardiovascular r...

    Authors: In Cheol Hwang, Yong Joo Lee, Hong Yup Ahn and Sang Min Lee

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:5

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  12. Content type: Review

    Human African trypanosomiasis due to Trypanosoma brucei rhodesiense is invariably fatal if untreated with up to 12.3 million people at a risk of developing the disease in Sub-Saharan Africa. The disease is charac...

    Authors: Charles D. Kato, Enock Matovu, Claire. M. Mugasa, Ann Nanteza and Vincent P. Alibu

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:4

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  13. Content type: Case report

    Polyethylene glycol is a ubiquitous, water-soluble, organic compound found in a wide variety of commercially available products. While generally a benign substance, in rare instances, it can induce hypersensit...

    Authors: Baruch D. Jakubovic, Corey Saperia and Gordon L. Sussman

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:3

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  14. Content type: Review

    The great majority (60–80 %) of patients consulting specialist physicians for allergic respiratory disease are polysensitized and thus may be potentially clinically polyallergic. However, management approaches...

    Authors: Pascal Demoly, Giovanni Passalacqua, Oliver Pfaar, Joaquin Sastre and Ulrich Wahn

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:2

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  15. Content type: Research

    Sensitization to aeroallergens increases the risk of developing asthma or allergic rhinitis. Data on sensitization to airborne allergens in the general population in sub-Saharan Africa are lacking. The aim of ...

    Authors: Bertrand Hugo Mbatchou Ngahane, Diane Noah, Malea Nganda Motto, Yacouba Mapoure Njankouo and Louis Richard Njock

    Citation: Allergy, Asthma & Clinical Immunology 2016 12:1

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  16. Content type: Research

    Previous studies have reported that up to 75 % of milk allergic subjects tolerate heated milk products. However, the food used for heated milk challenge is often prepared in a non-standardized manner by the pa...

    Authors: Sabrine Cherkaoui, Philippe Bégin, Louis Paradis, Jean Paradis and Anne Des Roches

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:39

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  17. Content type: Review

    The human microbiome can be defined as the microorganisms that reside within and on our bodies and how they interact with the environment. Recent research suggests that numerous mutually beneficial interaction...

    Authors: Amund Riiser

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:35

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  18. Content type: Case report

    Flare-up of allergic rhinitis has been implicated in worsening neuropsychiatric symptoms such as hyperactivity and anxiety in the general population, mostly supported by epidemiological data. However, it is un...

    Authors: Harumi Jyonouchi

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:38

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  19. Content type: Research

    Long pentraxin 3 (PTX3) is a novel candidate marker for inflammation in many chronic diseases. As a soluble pattern recognition receptor, PTX3 is involved in amplification of inflammatory reactions and regulat...

    Authors: Jingbo Zhang, Latifa Koussih, Lianyu Shan, Andrew J. Halayko, Ben-Kuen Chen and Abdelilah S. Gounni

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:37

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  20. Content type: Research

    Few population-based studies have assessed the prevalence and the risk factors of non-allergic rhinitis (NAR) in comparison to allergic rhinitis (AR). Moreover, epidemiologic data on rhinitis in the elderly su...

    Authors: Lucia Cazzoletti, Marcello Ferrari, Mario Olivieri, Giuseppe Verlato, Leonardo Antonicelli, Roberto Bono, Lucio Casali, Isa Cerveri, Pierpaolo Marchetti, Pietro Pirina, Andrea Rossi, Simona Villani and Roberto de Marco

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:36

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  21. Content type: Research

    A history of penicillin allergy in patients is common, but only 10–15 % are truly allergic. While the gold standard for diagnosing penicillin allergy is challenge, it is not recommended that this be done witho...

    Authors: Lana Rosenfield, Chrystyna Kalicinsky and Richard Warrington

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:34

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  22. Content type: Research

    Chronic rhinosinusitis with nasal polyps is characterized by local inflammation and is categorized into two subtypes in Japan: eosinophilic chronic rhinosinusitis, and non-eosinophilic chronic rhinosinusitis....

    Authors: Shintaro Baba, Ryoji Kagoya, Kenji Kondo, Maho Suzukawa, Ken Ohta and Tatsuya Yamasoba

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:33

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  23. Content type: Research

    Peanuts contain potent food allergens and the prevalence of allergy is reported to increase, especially in children. Since peanut sensitization may differ between different geographical regions, we wanted to i...

    Authors: Ellen Namork and Berit A. Stensby

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:32

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  24. Content type: Review

    Allergic diseases such as asthma and allergic rhinitis constitute a significant burden of disease among women of childbearing age and those who are pregnant. Adequately managing these conditions is paramount i...

    Authors: Paul Oykhman, Harold L. Kim and Anne K. Ellis

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:31

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  25. Content type: Research

    Many types of shellfish including oysters are sometime cooked before ingestion and it has been demonstrated that cooking may affect the allergenicity of food. Therefore, the aim of our present study is to iden...

    Authors: Zailatul Hani Mohamad Yadzir, Rosmilah Misnan, Faizal Bakhtiar, Noormalin Abdullah and Shahnaz Murad

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:30

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  26. Content type: Case report

    Denosumab is a human monoclonal antibody indicated for the treatment of osteoporosis in postmenopausal women with a high risk of fractures. To our knowledge, no cases of desensitization to this drug have been ...

    Authors: D. Gutiérrez-Fernández, María-Jesús Cruz, A. Foncubierta-Fernández, A. Moreno-Ancillo, M. J. Fernández-Anguita, F. Medina-Varo and J. A. Andres-García

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:29

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  27. Content type: Research

    The knowledge of general practitioner(s) (GPs) regarding food allergy and anaphylaxis and practices in the prescription of epinephrine auto-injector(s) (EAIs) among GPs has previously only been studied using q...

    Authors: Jacquelien Saleh-Langenberg, A. E. J. Dubois, F. Groenhof, J. W. H. Kocks, T. van der Molen and B. M. J. Flokstra-de Blok

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:28

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  28. Content type: Research

    New therapeutic approaches with biologic agents such as anti-cytokine antibodies are currently on trial for the treatment of asthma, rhinosinusitis or allergic diseases necessitating patient selection by bioma...

    Authors: Katrin König, Christine Klemens, Katharina Eder, Marion San Nicoló, Sven Becker, Matthias F. Kramer and Moritz Gröger

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:26

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  29. Content type: Research

    Ethyl-chloride (EC) spray was recently shown to be an effective antipruritic agent, when given 15 min after histamine skin-prick test (SPT), without changing the wheal and flare reaction. We aimed to investiga...

    Authors: Amir Gal-Oz, Shmuel Kivity, Yacov Shacham, Elisheva Fiszer, Ori Rogowsky and Gil Chernin

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:25

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  30. Content type: Research

    The World Allergy Organization estimates that 40 % of the world’s population is affected by allergic diseases. The International Study of Asthma and Allergies in Childhood has completed Phase III and it has no...

    Authors: Magali Herrant, Cheikh Loucoubar, Sabah Boufkhed, Hubert Bassène, Fatoumata Diene Sarr, Laurence Baril, Odile Mercereau-Puijalon, Salaheddine Mécheri, Anavaj Sakuntabhai and Richard Paul

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:24

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  31. Content type: Position article and guidelines

    The purpose of this brief communication is to highlight emerging evidence to existing guidelines regarding potential benefits of supporting early, rather than delayed, peanut introduction during the period of ...

    Authors: David M. Fleischer, Scott Sicherer, Matthew Greenhawt, Dianne Campbell, Edmond S. Chan, Antonella Muraro, Susanne Halken, Yitzhak Katz, Motohiro Ebisawa, Lawrence Eichenfield and Hugh Sampson

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:23

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  32. Content type: Case Report

    The aetiology of anaphylaxis ranges from food, insect venom, drugs and various chemicals. Some individuals do not develop anaphylaxis with the offending agent unless ingestion is related temporally to physical...

    Authors: Nilhan Rajiva de Silva, Wasala Mudiyanselage Dhanushka Kumari Dasanayake, Chandima Karunatilleke and Gathsauri Neelika Malavige

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:22

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  33. Content type: Research

    Omalizumab is approved in the UK as add-on treatment for chronic spontaneous urticaria (CSU) in patients with inadequate response to H1-antihistamines. Ciclosporin is an established but unlicensed 3rd line optio...

    Authors: Sinisa Savic, Alexander Marsland, David McKay, Michael R Ardern-Jones, Tabi Leslie, Olivier Somenzi, Laura Baldock and Clive Grattan

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:21

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  34. Content type: Review

    Epinephrine (adrenaline) is the treatment of choice for anaphylaxis. While other medications, including H1-antihistamines, H2-antihistamines, corticosteroids, and inhaled beta-2 agonists are often used to treat a...

    Authors: Michelle Halbrich, Douglas P. Mack, Stuart Carr, Wade Watson and Harold Kim

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:20

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  35. Content type: Research

    Allergy immunotherapy is an effective treatment for patients with allergic rhinitis whose symptoms are unresolved with pharmacotherapy. Allergy immunotherapy for grass pollen-induced allergic rhinitis is avail...

    Authors: Amanda L. McDonell, Ulrich Wahn, Dirk Demuth, Catrina Richards, Charlie Hawes, Jakob Nørgaard Andreasen and Felicia Allen-Ramey

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:19

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  36. Content type: Case report

    Rush oral immunotherapy (OIT) combined with omalizumab (OMB) has been reported to be an effective and safe treatment for severe milk allergies. However, no report has described long-term follow-up observations...

    Authors: Masaya Takahashi, Shoichiro Taniuchi, Kazuhiko Soejima, Yasuko Hatano, Sohsaku Yamanouchi and Kazunari Kaneko

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:18

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  37. Content type: Research

    A patient’s knowledge of his/her allergic condition and treatment is a key factor in adherence and effectiveness.

    Authors: Moises A. Calderon, Linda Cox, Thomas B. Casale, Ralph Mösges, Oliver Pfaar, Hans-Jørgen Malling, Joaquin Sastre, Musa Khaitov and Pascal Demoly

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:17

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  38. Content type: Research

    The Nasal Allergen Challenge (NAC) model allows the study of Allergic Rhinitis (AR) pathophysiology and the proof of concept of novel therapies. The Allergic Rhinitis – Clinical Investigator Collaborative (AR-...

    Authors: Anne K Ellis, Mena Soliman, Lisa Steacy, Marie-Ève Boulay, Louis-Philippe Boulet, Paul K Keith, Harissios Vliagoftis, Susan Waserman and Helen Neighbour

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:16

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  39. Content type: Retraction Note

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:15

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    The original article was published in Allergy, Asthma & Clinical Immunology 2014 10:A48

  40. Content type: Research

    Determining the cellular and molecular phenotypes of inflammation in asthma can identify patient populations that may best benefit from targeted therapies. Although elevated IL-6 and polymorphisms in IL-6 sign...

    Authors: Derek K Chu, Amal Al-Garawi, Alba Llop-Guevara, Regina A Pillai, Katherine Radford, Pamela Shen, Tina D Walker, Susanna Goncharova, William J Calhoun, Parameswaran Nair and Manel Jordana

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:14

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  41. Content type: Research

    Sensitization to flour or fungal alpha-amylase is a prerequisite for the development of respiratory allergy in bakers. The knowledge of occupational allergen sensitization among bakery workers will facilitate ...

    Authors: Bertrand Hugo Mbatchou Ngahane, Francis Nde, Eliane Ngomo and Emmanuel Afane Ze

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:13

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  42. Content type: Research

    Asthma remains an uncontrolled disease. The Comorbidities, particularly obesity, and several other factors have been identified as being individually associated with asthma control, and these factors vary amon...

    Authors: Albertina Varandas Capelo, Vania Matos de Fonseca, Maria Virgínia Marques Peixoto, Sonia Regina de Carvalho and Larissa Garcia Guerino

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:12

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  43. Content type: Review

    TRPA1 has been proposed to be associated with diverse sensory allergic reactions, including thermal (cold) nociception, hearing and allergic inflammatory conditions. Some naturally occurring compounds are know...

    Authors: Satoru Mihara and Takayuki Shibamoto

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:11

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  44. Content type: Case report

    Allergic reactions to legumes are common.Food allergy to cooked, but not raw, pea has been rarely reported in the literature. This case series describes five children who had various IgE-mediated symptoms upon...

    Authors: Elissa M Abrams and Thomas V Gerstner

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:10

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  45. Content type: Position article and guidelines

    Asthma is a chronic inflammatory disease of the airways that affects a growing number of children and adolescents. Inhaled corticosteroids (ICS) are the mainstay of treatment in persistent asthma, with a stepw...

    Authors: Karine Issa-El-Khoury, Harold Kim, Edmond S Chan, Tim Vander Leek and Francisco Noya

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:9

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  46. Content type: Research

    Symptoms of allergic rhinitis (AR) have a detrimental effect on quality of life. The AR-Patient Benefit Index (AR-PBI), a specific self-assessment tool has been developed to assess treatment-related benefit in...

    Authors: Pascal Demoly, Michel Aubier, Frédéric de Blay, François Wessel, Pierre Clerson and Pascal Maigret

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:8

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  47. Content type: Review

    In the past few years there have been significant advances which have changed the face of chronic urticaria. In this review, we aim to update physicians about clinically relevant advances in the classification...

    Authors: Gordon Sussman, Jacques Hébert, Wayne Gulliver, Charles Lynde, Susan Waserman, Amin Kanani, Moshe Ben-Shoshan, Spencer Horemans, Carly Barron, Stephen Betschel, William H Yang, Jan Dutz, Neil Shear, Gina Lacuesta, Peter Vadas, Kenneth Kobayashi…

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:7

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  48. Content type: Reviewer acknowledgement

    The editors of Allergy, Asthma & Clinical Immunology would like to thank all of our reviewers who have contributed to the journal in Volume 10 (2014).

    Authors: Richard Warrington

    Citation: Allergy, Asthma & Clinical Immunology 2015 11:6

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