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  1. Allergic respiratory diseases such as allergic rhinitis (AR) and allergic asthma (AA) are common conditions that can influence sleep and daytime functioning. However, the significance of this impact is unclear...

    Authors: Mercedes Rodriguez Romano, Stephanie James, Emily Farrington, Richard Perry and Lisa Elliott

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:81

    Content type: Research

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  2. Allergy to Vespa affinis venom is common in the Asia Pacific region. Venom preparations for diagnosis are not commercially available for this species.

    Authors: Peshala Gunasekara, S. M. Handunnetti, Sunil Premawansa, Pradeep Kaluarachchi, Chandima Karunatilake, Indra P. Ratnayake, R. K. S. Dias, G. A. S. Premakumara, W. M. D. K. Dasanayake, Suranjith L. Seneviratne and Rajiva de Silva

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:80

    Content type: Research

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  3. We showed previously that allergic reactivity to ovalbumin (OVA) could be regulated in mice following perturbation of immune networks using combinations of an immune Ig along with anti-idiotypic Ig. We have ex...

    Authors: R. M. Gorczynski, T. Maqbool and G. Hoffmann

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:79

    Content type: Research

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  4. Common variable immunodeficiency disorders (CVID) are a rare group of primary immune defects, where the underlying cause is unknown. Approximately 10–20% of patients with typical CVID have a granulomatous vari...

    Authors: Rohan Ameratunga, Yeri Ahn, Dominic Tse, See-Tarn Woon, Jennifer Pereira, Sinead McCarthy and Hilary Blacklock

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:78

    Content type: Case report

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  5. Hymenoptera venom allergy is one of the most frequent causes of anaphylaxis. In its most severe form, the reaction to wasp and honey bee stings may be life-threatening. Therefore, immediate and proper diagnosis o...

    Authors: Eliza Matuszewska, Joanna Matysiak, Anna Bręborowicz, Katarzyna Olejniczak, Zdzisława Kycler, Zenon J. Kokot and Jan Matysiak

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:77

    Content type: Research

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  6. There are numerous biologics for treating patients with severe asthma. A cost-effective method for selecting the most appropriate biologic therapy for a patient is thus important. Bronchoscopy-guided bronchial...

    Authors: Chin-Wei Kuo, Xin-Min Liao, Yi-Ching Huang, Han-Yu Chang and Chi-Chang Shieh

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:76

    Content type: Case report

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  7. The concept of the unified allergic airway disease (UAD) recognises the association between allergic inflammation in the upper and lower airways. Patients with asthma and concomitant allergic rhinitis experien...

    Authors: Chris RuiWen Kuo, Rory Chan and Brian Lipworth

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:75

    Content type: Letter to the editor

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  8. This study examined whether infants aged 0–3 months exhibited long-term effects of using a moisturizer skincare intervention and whether a short-term skin problem resulted in the subsequent development of food...

    Authors: Kaori Yonezawa and Megumi Haruna

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:74

    Content type: Research

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  9. Allergen inhalation tests are a valuable research tool. The allergen dose producing an early asthmatic response (EAR) can be predicted from methacholine responsiveness and allergen skin test endpoint (STE). Th...

    Authors: Donald W. Cockcroft, Beth E. Davis, Christianne M. Blais, Louis-Philippe Boulet, Marie-Éve Boulay, Hélène Villeneuve, Gail M. Gauvreau, Paul M. O’Byrne, Karen J. Howie and Caitlin D. Obminski

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:73

    Content type: Research

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  10. This is an update to the 2014 Canadian Hereditary Angioedema Guideline with an expanded scope to include the management of hereditary angioedema (HAE) patients worldwide. It is a collaboration of Canadian and ...

    Authors: Stephen Betschel, Jacquie Badiou, Karen Binkley, Rozita Borici-Mazi, Jacques Hébert, Amin Kanani, Paul Keith, Gina Lacuesta, Susan Waserman, Bill Yang, Emel Aygören-Pürsün, Jonathan Bernstein, Konrad Bork, Teresa Caballero, Marco Cicardi, Timothy Craig…

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:72

    Content type: Review

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  11. This study was performed to determine whether there was any association between abnormal DNA methylation of a thymic stromal lymphopoietin (TSLP) locus and pathogenesis of chronic rhinosinusitis (CRS).

    Authors: Jingyun Li, Jian Jiao, Yunbo Gao, Yuan Zhang and Luo Zhang

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:71

    Content type: Research

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  12. The National Review of Asthma Deaths UK highlighted that 46% of deaths could be avoided and recommended that all sufferers receive a structured asthma annual review which assess asthma control. In primary care...

    Authors: Raj Gill and E. Mark Williams

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:70

    Content type: Research

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  13. In this paper, we review methodological approaches used in studies that evaluated the association between occupational exposure to quaternary ammonium compounds (quats) and occupational asthma. This associatio...

    Authors: Judy S. LaKind and Michael Goodman

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:69

    Content type: Review

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  14. Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder caused by a defect in the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. The disease primarily presents wit...

    Authors: Suzan AlKhater

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:68

    Content type: Case report

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  15. Blood has proven to be a useful resource for molecular analysis in numerous biomedical studies, with peripheral blood mononuclear cells (PBMCs) and whole blood being the major specimen types. However, comparat...

    Authors: Daniel He, Chen Xi Yang, Basak Sahin, Amrit Singh, Casey P. Shannon, John-Paul Oliveria, Gail M. Gauvreau and Scott J. Tebbutt

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:67

    Content type: Research

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  16. Hereditary angioedema with normal C1 inhibitor (HAE-nC1 INH) is a rare, underappreciated condition characterized by recurrent subcutaneous angioedema. The underlying pathophysiology and diagnostic criteria con...

    Authors: Lundy McKibbin, Colin Barber, Chrystyna Kalicinsky and Richard Warrington

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:66

    Content type: Research

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  17. Gender differences in asthma perception and control have been reported. The PROXIMA observational study assessed these outcomes in a cohort of Italian severe allergic asthma (SAA) patients. This post hoc analy...

    Authors: Delia Colombo, Emanuela Zagni, Fabio Ferri and Giorgio Walter Canonica

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:65

    Content type: Research

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  18. Monocytes play an important role in immune and inflammatory diseases and monocyte subsets are predictors of disease in certain conditions. Expression of the chemokine receptors, CCR2 and CX3CR1 on monocyte subset...

    Authors: Reem Al-Rashoudi, Gillian Moir, Mohamed S. Al-Hajjaj, Monther M. Al-Alwan, Heather M. Wilson and Isabel J. Crane

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:64

    Content type: Research

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  19. Immunological Human African Trypanosomiasis (HAT) studies often exclude malaria, although both infections overlap in specific endemic areas. During this co-infection, it is not known whether this parasitic int...

    Authors: Julius Nsubuga, Charles Drago Kato, Ann Nanteza, Enock Matovu and Vincent Pius Alibu

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:63

    Content type: Research

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  20. Investigating the association between caesarean section (SC) and childhood asthma has shown contradictory results in different studies. The present study was conducted to determine the association between SC a...

    Authors: Behzad Darabi, Shoboo Rahmati, Mohammad Reza HafeziAhmadi, Gholamreza Badfar and Milad Azami

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:62

    Content type: Review

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  21. Oral H1-antihistamines (AHs) are the most commonly used therapy to treat allergic rhinitis and chronic urticaria. Older, first-generation AHs (e.g. diphenhydramine, hydroxyzine) have significant and common side e...

    Authors: Michael N. Fein, David A. Fischer, Andrew W. O’Keefe and Gord L. Sussman

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:61

    Content type: Review

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  22. To assess the safety and efficacy of an oral immunotherapy regimen in patients with allergy to lipid transfer proteins (LTPs).

    Authors: Begoña Navarro, Eladia Alarcón, Ángela Claver, Mariona Pascal, Araceli Díaz-Perales and Anna Cisteró-Bahima

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:60

    Content type: Short report

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  23. Despite advances in treating Systemic lupus erythematosus (SLE), a proportion of patients continue to face significant morbidity and mortality. Haemopoietic stem cell transplant (HSCT) has been recognized as a...

    Authors: Nipun Lakshitha de Silva and Suranjith L. Seneviratne

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:59

    Content type: Review

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  24. Allergic rhinitis (AR) is one of the most common diseases globally and usually persists throughout life. In the present study, we aimed to determine whether the expression of inflammatory biomarkers has a rela...

    Authors: Myung Woul Han, Song Hee Kim, Inbo Oh, Yang Ho Kim and Jiho Lee

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:58

    Content type: Research

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  25. Associations between allergic disease and puberty amongst females have been widely studied. However, this association has received less attention in multigenerational populations. To this end, we sought to exa...

    Authors: Jennifer Lisa Penner Protudjer, Elissa Michelle Abrams, Anita Luba Kozyrskyj and Allan Barry Becker

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:57

    Content type: Letter to the editor

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  26. The incidence of chronic rhinosinusitis with nasal polyps has recently increased in Japan and other East Asian countries, and this disease is called eosinophilic chronic sinusitis (ECRS) in Japan. ECRS usually...

    Authors: Yasuho Shoda, Misa Watanabe, Kota Wada, Takehiko Soutome, Yumiko Komine, Tetsuo Mikami, Tetsuo Nemoto and Akira Ohara

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:55

    Content type: Case report

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  27. Compared to non-allergic individuals, food allergic individuals have impaired health-related quality of life (HRQL). However, effects of gender and age are unclear. The objective of our study was to describe a...

    Authors: Jennifer Lisa Penner Protudjer, Roelinde Middelveld, Sven-Erik Dahlén and Staffan Ahlstedt

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:54

    Content type: Research

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  28. Adolescents (12–17 years of age) with severe eosinophilic asthma experience frequent exacerbations and reduced lung function leading to poor health-related quality of life. Mepolizumab is approved for add-on m...

    Authors: Steven W. Yancey, Hector G. Ortega, Oliver N. Keene and Eric S. Bradford

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:53

    Content type: Letter to the editor

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  29. Increasing prevalence of childhood allergic diseases including asthma is a global health concern, and we aimed to investigate prenatal risk factors for childhood asthma and to address the potential shared pren...

    Authors: Ching-Heng Lin, Jiun-Long Wang, Hsin-Hua Chen, Jeng-Yuan Hsu and Wen-Cheng Chao

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:52

    Content type: Research

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  30. The full range of allergic reactions to Total Parenteral Nutrition (TPN) remains unknown. Additionally, beyond individual allergens, there may be other factors contributing to TPN hypersensitivity reactions.

    Authors: Steph A. Pang, Shaun Eintracht, Jesse M. Schwartz, Belinda Lobo and Elizabeth MacNamara

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:51

    Content type: Case report

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  31. There is interest in better understanding vessel pathology in asthma, given the findings of loss of peripheral vasculature associated with disease severity by imaging and altered markers of endothelial activat...

    Authors: Renata Calciolari Rossi, Raquel Anonni, Diogenes Seraphim Ferreira, Luiz Fernando Ferraz da Silva and Thais Mauad

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:50

    Content type: Research

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  32. Hereditary angioedema (HAE) is a debilitating disorder resulting from C1-esterase inhibitor (C1-INH) deficiency. In the COMPACT phase 3 study the prophylactic use of a subcutaneous C1 inhibitor (C1-INH [SC], H...

    Authors: H. Henry Li, Bruce Zuraw, Hilary J. Longhurst, Marco Cicardi, Konrad Bork, James Baker, William Lumry, Jonathan Bernstein, Michael Manning, Donald Levy, Marc A. Riedl, Henrike Feuersenger, Subhransu Prusty, Ingo Pragst, Thomas Machnig and Timothy Craig

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:49

    Content type: Research

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  33. Asthma is often accompanied by peripheral eosinophilia and eosinophilic airway inflammation. This article explores the relationship between asthma and short-term pulmonary infiltrate with eosinophilia, which r...

    Authors: Min Song, Shan Cai, Hong Luo, Yi Jiang, Min Yang, Yan Zhang, Hong Peng and Ping Chen

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:48

    Content type: Case report

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  34. The lymphohematopoietic cells originating from feto-maternal trafficking during pregnancy may cause microchimerism and lead to materno-fetal graft versus host disease (GVHD) in severe combined immunodeficiency...

    Authors: Zahra Shahbazi, Nima Parvaneh, Shirin Shahbazi, Hamzeh Rahimi, Mohammad Hamid, Davoud Shahbazi, Samaneh Delavari, Hassan Abolhassani, Asghar Aghamohammadi and Reza Mahdian

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:47

    Content type: Case report

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  35. Asthma is a chronic disease that seriously harms the health of patients. Oxidative stress is involved in asthma. As an oxidative stress-inducible protein, sestrin2 is elevated in oxidative stress-related disea...

    Authors: Yanfang Kang, Chen Chen, Xiaotian Hu, Xiaohua Du, Huifen Zhai, Yan Fang, Xiulin Ye, Weimin Yang and Shibo Sun

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:46

    Content type: Research

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  36. Neutrophils play an important role in the pathogenesis of rheumatoid arthritis (RA). It has recently been reported that in addition to T helper (Th) 17 cells, other cells, including neutrophils, produce IL-17A...

    Authors: Maria Gonzalez-Orozco, Rosa E. Barbosa-Cobos, Paola Santana-Sanchez, Lizbeth Becerril-Mendoza, Leonardo Limon-Camacho, Ana I. Juarez-Estrada, Gustavo E. Lugo-Zamudio, Jose Moreno-Rodriguez and Vianney Ortiz-Navarrete

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:44

    Content type: Research

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  37. To identify novel epigenetic markers of adolescent asthma and replicate findings in an independent cohort, then explore whether such markers are detectable at birth, predictive of early-life wheeze, and associ...

    Authors: Todd M. Everson, Hongmei Zhang, Gabrielle A. Lockett, Akhilesh Kaushal, Melinda Forthofer, Susan L. Ewart, Kimberley Burrows, Caroline L. Relton, Gemma C. Sharp, A. John Henderson, Veeresh K. Patil, Faisal I. Rezwan, S. Hasan Arshad, John W. Holloway and Wilfried Karmaus

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:43

    Content type: Research

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  38. Allergic diseases are increasing yearly. We aimed to evaluate the difference in allergen sensitization pattern between adults and children in southern China by analyzing a large sample size of real-life data, ...

    Authors: Wenting Luo, Haisheng Hu, Wangbing Tang, Xiangwei Zou, Huimin Huang, Zhifeng Huang, Yong Liu and Baoqing Sun

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:42

    Content type: Research

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  39. It is known that small airway disease is present across all asthma severities; however, its prevalence and clinical characteristics in cough variant asthma (CVA) have not been fully illuminated.

    Authors: Honglei Yuan, Xiaojing Liu, Li Li, Gang Wang, Chunfang Liu, Yuzhen Zeng, Ruolin Mao, Chunling Du and Zhihong Chen

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:41

    Content type: Research

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  40. Consumption of certain foods during pregnancy has been shown to have beneficial effects on childhood asthma and allergic disease development and aggravation. However, most studies provide conflicting results a...

    Authors: Nour Baïz, Jocelyne Just, Julie Chastang, Anne Forhan, Blandine de Lauzon-Guillain, Anne-Marie Magnier and Isabella Annesi-Maesano

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:40

    Content type: Research

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  41. The pathogenesis and etiology of antrochoanal polyps (ACPs) remains obscure. This study aimed to characterize the inflammatory profiles and investigate the effect of atopy on the pathogenesis of pediatric ACPs.

    Authors: Huiwen Zheng, Lixing Tang, Beibei Song, Xiaojian Yang, Ping Chu, Shujing Han, Pengpeng Wang, Jie Lu, Wentong Ge and Xin Ni

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:39

    Content type: Research

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  42. Nearly all the investigations into the risk factors for wheezing and asthma were conducted in developed countries with a high prevalence rate of asthma and allergy, but the studies in developing countries are ...

    Authors: Jing Guo, Wenjing Zhu, Huimin Wang, Patrick G. Holt, Guicheng Zhang and Chuanhe Liu

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:38

    Content type: Research

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  43. Limited information is available on the clinical course of patients with severe asthma following discontinuation of biologic treatment. Therefore, a post hoc analysis was conducted in patients with severe eosi...

    Authors: Hector Ortega, Catherine Lemiere, Jean-Pierre Llanos, Mark Forshag, Robert Price, Frank Albers, Steven Yancey and Mario Castro

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:37

    Content type: Letter to the editor

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  44. Allergic bronchopulmonary aspergillosis (ABPA) and allergic fungal rhinosinusitis (AFRS) are characterized by hyper-responsiveness of the respiratory tract and the nasal cavity and paranasal sinuses, respectiv...

    Authors: Eisuke Mochizuki, Shun Matsuura, Tsutomu Kubota, Yasutaka Mochizuka, Kyohei Oishi, Hyogo Naoi, Masahiro Uehara, Shinichiro Mikura, Miyuki Nagaoka, Masaru Tsukui, Naoki Koshimizu and Ichirota Nameki

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:35

    Content type: Case report

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  45. Idiopathic systemic capillary leak syndrome (ISCLS), is a rare disorder characterized by recurrent attacks of varying severity of hypovolemic shock and generalized edema in association with hemoconcentration a...

    Authors: Ahmed M. Alkhunaizi, Abdullah H. Kabbani and Mohamed A. ElTigani

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:34

    Content type: Case report

    Published on:

  46. MicroRNA-21 (miR-21), probably one of the most studied miRNAs to date, is found pleiotropic in various biological events. Its emerging role in pulmonary remodeling has attracted extensive attention. This revie...

    Authors: Congshan Jiang, Yuanxu Guo, Hongchuan Yu, Shemin Lu and Liesu Meng

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:33

    Content type: Review

    Published on:

  47. Hereditary angioedema (HAE) is a potentially life-threatening group of conditions that is often underdiagnosed or misdiagnosed. As HAE is typically diagnosed by detecting C1 inhibitor deficiency, there is a cr...

    Authors: Dale L. Bodian, Thierry Vilboux and Natalie S. Hauser

    Citation: Allergy, Asthma & Clinical Immunology 2019 15:32

    Content type: Case report

    Published on:

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